1.
Org Lett
; 12(15): 3567-9, 2010 Aug 06.
Article
in English
| MEDLINE
| ID: mdl-20670021
ABSTRACT
A simple and straightforward method has been developed for the direct carboxylation of aromatic heterocycles such as oxazoles, thiazoles, and oxadiazoles using CO(2) as the C1 source. The reactions require no metal catalyst and only Cs(2)CO(3) as the base. A good functional group tolerance is achieved.