Subject(s)
Aneurysm/diagnostic imaging , Echocardiography, Three-Dimensional , Echocardiography, Transesophageal , Heart Valve Diseases/diagnostic imaging , Mitral Valve/diagnostic imaging , Aneurysm/surgery , Aortic Valve/diagnostic imaging , Aortic Valve/surgery , Diagnosis, Differential , Endocarditis, Bacterial/diagnostic imaging , Endocarditis, Bacterial/surgery , Female , Heart Valve Diseases/surgery , Heart Valve Prosthesis Implantation , Humans , Middle Aged , Mitral Valve/surgery , Multidetector Computed Tomography , Pericardium/transplantation , Sensitivity and Specificity , Streptococcal Infections/diagnostic imaging , Streptococcal Infections/surgery , Streptococcus mutansABSTRACT
We report a 70-year-old patient with sarcoidosis associated with psoriasis vulgaris. He had a nodule on the medial lower lid of his right eye. Oral corticosteroid for the sarcoid lesions and oral PUVA for psoriasis were employed. The cutaneous lesion disappeared within two months after starting the therapy. No relapse of sarcoidosis has been seen for eight years. The association of sarcoidosis with psoriasis has been previously reported; however, it is still unclear whether this association coincidental or meaningful.
Subject(s)
Granuloma, Giant Cell/diagnosis , Psoriasis/diagnosis , Sarcoidosis, Pulmonary/diagnosis , Aged , Diagnosis, Differential , Eyelids , Glucocorticoids/therapeutic use , Granuloma, Giant Cell/complications , Granuloma, Giant Cell/drug therapy , Granuloma, Giant Cell/pathology , Humans , Male , PUVA Therapy , Prednisolone/therapeutic use , Psoriasis/complications , Psoriasis/drug therapy , Psoriasis/pathology , Sarcoidosis, Pulmonary/complications , Sarcoidosis, Pulmonary/drug therapy , Sarcoidosis, Pulmonary/pathology , Skin Diseases/complications , Skin Diseases/diagnosis , Skin Diseases/drug therapy , Skin Diseases/pathologyABSTRACT
We report a patient with the Cockayne and Touraine type epidermolysis bullosa dystrophica domains. A 6-year-old Japanese female developed blisters and erosions on the extremities 3 months after birth. Immunohistology showed a linear binding pattern of the monoclonal antibody against type VII collagen (LH:2) on the epidermal basement membrane. By means of electron microscopy and morphometric analysis, it became apparent that the anchoring fibrils were rudimentary in structure and reduced in number.
