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Internist (Berl) ; 58(10): 1097-1101, 2017 Oct.
Article in German | MEDLINE | ID: mdl-28516249

ABSTRACT

A 67-year-old man presented with fever, night sweat and abdominal complaints for about 4 weeks. Ultrasound and a computed tomography scan showed distinct ascites as the main finding, presenting as exsudate with predominating lymphoid cells. Because of long-term immunosuppressive therapy with the tumor necrosis factor (TNF)-α inhibitor golimumab for psoriasis, the suspicion for a possible tuberculous peritonitis arose. This was confirmed with an enzyme-linked immunospot assay, a high level of adenosine deaminase in the ascites and a peritoneum which was studded with multiple whitish nodules, corresponding to granulomas with giant cells. With a standard antituberculous regimen the symptoms were quickly relieved and finally complete restitution was achieved.


Subject(s)
Antibodies, Monoclonal/adverse effects , Ascites/etiology , Fever of Unknown Origin/etiology , Peritonitis, Tuberculous/chemically induced , Psoriasis/drug therapy , Sweating , Adenosine Deaminase/metabolism , Aged , Antibodies, Monoclonal/therapeutic use , Circadian Rhythm , Diagnosis, Differential , Enzyme-Linked Immunospot Assay , Humans , Male , Peritonitis, Tuberculous/diagnosis
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