[Phase changes of energy metabolism during adaptation to immobilization stress].

In stress, it was showed the organ and tissue changes associated with damage by lipid peroxides, and the disrupted barrier function. As a consequence, it was to lead to a syndrome of "stress-induced lung" and violation of oxygen delivery to the tissues and hypoxia. Purpose of the study was to investigate the dynamics of changes in gas exchange, blood glucose, body temperature, oxidant and antioxidant system activity, as well as mitochondrial respiration by Chance under the influence of chronic stress (6-hour immobilization daily for 3 weeks). It was identified 4 phase changes of energy metabolism in the dynamics of chronic stress. In the first phase, hypomethabolic, instability oxidative metabolism, decreased oxidation of NAD-dependent substrates, significant elevation of FAD-dependent substrates oxidation and low MRU were found. The activity of superoxide dismutase (MnSOD) was increased; it was occurred on a background low activity of glutathione peroxidase, and of misbalanced antioxidant system. After seven immobilizations, second phase-shift in energy metabolism, was observed, and then the third phase (hypermetabolic) started. It was characterized by gradual increase in oxidative metabolism, the restoration of oxidation of NAD-dependent substrates, MRU, as well as optimizing balance of oxidant and antioxidant systems. The fourth phase was started after 15 immobilizations, and characterized by the development of adaptive reactions expressed in increased tolerance of energy metabolism to the impact of immobilization. The results are correlated with changes in the dynamics of blood corticosterone. Thus, it was found the phase character of the energy metabolism rebuilding during the chronic stress.

[Physical development and formation of psychophysiological functions in young school-age children]. / Fizychnyi rozvytok i formuvannia psykhofiziolohichnyk funktsii u ditei molodshoho shkil'noho viku.

The aim of investigation was to study of physical development and psychophysiological functions forming in children of young school age. Were studied 25 schoolchildren (12 girls and 13 boys) in 4 class of average school. Anthropometric and functional parameters as level of physical development were studied. In dynamics of school year were studied of psychic functions. The investigations are showed that process of learning provokes of fatigue and reflects on psychic functions efficiency as well as negative influence on physical development. The psychic functions forming characterized to gradual mobilization of new elements of functional system during school year in children of young school age.

[The characteristics of the morphofunctional status of 15- to 17-year-old youths based on a comprehensive assessment of the rates of their biological development]. / Osoblyvosti morfofunktsional'noho stanu iunakiv 15--17 rokiv na osnovi kompleksnoï otsinky tempiv ïkh biolohichnoho rozvytku.

There were studied individual typological peculiarities of the genesis of the genesis of 15-17 years old boys, the state of their respiration and their heart activities. According to these experiments there was stated the possibility of the complex appreciation of the biological tempos of genesis of the senior grades' pupils on the bases of physical and somatic genesis and sexual maturity. As a result of such differentiation of 15-17 year old boys there will appear 3 typological groups--fast, normal and slow types of genesis which quite differ by the majority of grades. Besides these 3 groups differ by the functioning of cardiorespiratory system. Boys with fast tempos of genesis are closer by the functioning peculiarities of cardiorespiratory system to the normal tempos of genesis which are understudy. The group with the slow genesis is quite different from the groups with the fast and normal genesis.

[The adaptation of youth with different rates of morphofunctional development to physical loading]. / Adaptatsiia iunakiv z riznymy tempamy morfofunktsional'noho rozvytku do fizychnykh navantazhen'.

There were studied morphofunctional peculiarities of biological development of 15-17-year-old boys' organisms on the bases of complex use, for this, of the level of physical development, rates of sex maturity and somatotype. On that base there were studied the individual peculiarities of their adaptation to the physical loads, which was directed to the development of endurance. It was ascertained, that the boys of the examined age groups, based on the complex differentiation are divided into 3 basic groups--fast, normal and slow rates of genesis. These typological groups differ by the measure and quantity of periods of long-term adaptation, and by the nature of adaptable changes in the organisms which are studied as a result of influence of long-lasted dosing loads, directed to the development of endurance.