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Mycoses ; 59(11): 734-741, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27427490

ABSTRACT

Candida wangnamkhiaoensis is a species clustered under the Hyphopichia clade has not ever been isolated from any clinical specimens. To the best of our knowledge, this is the first report of C. wangnamkhiaoensis associated with fungaemia in immunocompromised paediatric patient. The isolate was assigned a strain name as UZ1679/14, in which the identification was confirmed by a polymerase chain reaction-sequencing of the internal transcribed spacer (ITS) and large subunit (LSU) regions of the rRNA gene. Antifungal susceptibility pattern showed that the isolate was sensitive to anidulafungin, caspofungin, fluconazole and voriconazole. The patient clinically improved after the antifungal treatment with caspofungin.


Subject(s)
Candida/isolation & purification , Candidemia/microbiology , Immunocompromised Host , Anidulafungin , Antifungal Agents/pharmacology , Candida/classification , Candida/genetics , Candida/ultrastructure , Candidemia/drug therapy , Candidemia/immunology , Caspofungin , Child, Preschool , DNA, Ribosomal Spacer , Echinocandins/pharmacology , Echinocandins/therapeutic use , Fluconazole/pharmacology , Humans , Hyphae/isolation & purification , Hyphae/ultrastructure , Lipopeptides/pharmacology , Lipopeptides/therapeutic use , Male , Phylogeny , Polymerase Chain Reaction , Sequence Alignment , Voriconazole/pharmacology
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