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Biomed Microdevices ; 11(3): 625-31, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19169826

ABSTRACT

We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD(3) (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD(3) provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD(3) are proposed.


Subject(s)
Ambulatory Care , Drug Delivery Systems/instrumentation , Emergency Medical Services , Infusion Pumps, Implantable , Micro-Electrical-Mechanical Systems , Equipment Design , Humans , Miniaturization , Time Factors , Vasoconstrictor Agents/therapeutic use , Vasopressins/therapeutic use
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