1.
Nutrients
; 12(3)2020 Mar 03.
Article
in English
| MEDLINE
| ID: mdl-32138282
ABSTRACT
The essential amino acid, methionine, is important for cancer cell growth and metabolism. A growing body of evidence indicates that methionine restriction inhibits cancer cell growth and may enhance the efficacy of chemotherapeutic agents. This review summarizes the efficacy and mechanism of action of methionine restriction on hallmarks of cancer in vitro and in vivo. The review highlights the role of glutathione formation, polyamine synthesis, and methyl group donation as mediators of the effects of methionine restriction on cancer biology. The translational potential of the use of methionine restriction as a personalized nutritional approach for the treatment of patients with cancer is also discussed.
Subject(s)
Methionine/metabolism , Neoplasms/diet therapy , Neoplasms/metabolism , Animals , Humans , Methionine/administration & dosage , Neoplasms/pathology
2.
US News World Rep
; 147(2): 30, 2010 Feb.
Article
in English
| MEDLINE
| ID: mdl-20128402
3.
US News World Rep
; 147(2): 32-7, 2010 Feb.
Article
in English
| MEDLINE
| ID: mdl-20128403
4.
US News World Rep
; 147(2): 46-7, 2010 Feb.
Article
in English
| MEDLINE
| ID: mdl-20128406
5.
US News World Rep
; 147(2): 50, 2010 Feb.
Article
in English
| MEDLINE
| ID: mdl-20128408
Subject(s)
Employment , Longevity , Health Status Disparities , Humans , Job Satisfaction , Personal Satisfaction , Social Class
6.
US News World Rep
; 147(11): 16, 19-20, 22, passim, 2010 Dec.
Article
in English
| MEDLINE
| ID: mdl-21604616
Subject(s)
Health Behavior , Personal Satisfaction , Quality of Life , Guidelines as Topic , Health Promotion , Humans
7.
US News World Rep
; 146(11): 38, 41, 2009 Dec.
Article
in English
| MEDLINE
| ID: mdl-20027817
8.
US News World Rep
; 146(11): 42, 44, 2009 Dec.
Article
in English
| MEDLINE
| ID: mdl-20027818
9.
US News World Rep
; 146(11): 52-4, 2009 Dec.
Article
in English
| MEDLINE
| ID: mdl-20027820
Subject(s)
Cancer Care Facilities , Neoplasms/therapy , Quality of Health Care , Expert Testimony , Humans , United States
10.
US News World Rep
; 146(11): 83-4, 2009 Dec.
Article
in English
| MEDLINE
| ID: mdl-20027831
11.
US News World Rep
; 146(11): 82-3, 2009 Dec.
Article
in English
| MEDLINE
| ID: mdl-20027830
12.
US News World Rep
; 146(9): 86, 2009 Oct.
Article
in English
| MEDLINE
| ID: mdl-19806876
Subject(s)
Exercise , Adult , Age Factors , Attitude to Health , Humans , Middle Aged , United States
13.
US News World Rep
; 146(7): 31-2, 2009 Aug.
Article
in English
| MEDLINE
| ID: mdl-19685763
Subject(s)
Embryonic Stem Cells , Adult Stem Cells , Biomedical Research , Cell Differentiation , Embryo Research , Humans , United States
14.
Critics take aim at high-tech care. Many expensive medical tools are valuable but arguably overused.
US News World Rep
; 146(7): 76, 78, 2009 Aug.
Article
in English
| MEDLINE
| ID: mdl-19685776
15.
US News World Rep
; 146(1): 44, 2009 Feb.
Article
in English
| MEDLINE
| ID: mdl-19554946
Subject(s)
Breast Neoplasms/prevention & control , Primary Prevention/methods , Adolescent , Child , Female , Humans , Middle Aged
16.
US News World Rep
; 146(1): 78-80, 2009 Feb.
Article
in English
| MEDLINE
| ID: mdl-19554962
17.
US News World Rep
; 146(1): 81-2, 2009 Feb.
Article
in English
| MEDLINE
| ID: mdl-19554963
18.
US News World Rep
; 145(7): 69, 2008.
Article
in English
| MEDLINE
| ID: mdl-19049011
19.
US News World Rep
; 145(10): 48-50, 53, 2008.
Article
in English
| MEDLINE
| ID: mdl-18998442
Subject(s)
Genetic Research , Genetics, Medical/trends , Medical Oncology/trends , Neoplasms/genetics , Neoplasms/therapy , Patient Care Planning/trends , Antineoplastic Agents/therapeutic use , Biomarkers, Tumor , Combined Modality Therapy , Drug Delivery Systems/trends , Humans , Neoplasms/diagnosis , Neoplastic Stem Cells/drug effects , Signal Transduction/drug effects
20.
US News World Rep
; 145(10): 53, 2008.
Article
in English
| MEDLINE
| ID: mdl-18998443
