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Ren Fail ; 29(6): 747-50, 2007.
Article in English | MEDLINE | ID: mdl-17763172

ABSTRACT

We report the case of a 62-year-old man without prodromal symptoms who developed a hemolytic-uremic syndrome (HUS) one week after the diagnosis of an acute bacteremic urinary infection (UTI). In this patient, the E. coli isolated in blood cultures was a non-O157:H7 Shigatoxin-producing strain that could subsequently be identified as O138:H-. This is a strain that is normally found in pigs and that has never been isolated in humans previously. UTI-related HUS is a rare event, as until now, only 14 pediatric and 3 adult cases have been reported. Indeed, this new case, besides its interesting microbiological aspects, should heighten our awareness of UTI-related HUS as a rare but real condition, not only in young children but also in adult patients. This should emphasize the necessity to search actively for other sources of Shigatoxin-producing E. coli in patients presenting with HUS without gastrointestinal symptoms.


Subject(s)
Escherichia coli Infections/microbiology , Escherichia coli/metabolism , Hemolytic-Uremic Syndrome/microbiology , Shiga Toxin/biosynthesis , Urinary Tract Infections/microbiology , Animals , Escherichia coli/isolation & purification , Hemolytic-Uremic Syndrome/complications , Humans , Male , Middle Aged , Sus scrofa/microbiology
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