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1.
Ann R Coll Surg Engl ; 68(4): 234, 1986 Jul.
Article in English | MEDLINE | ID: mdl-19311100
3.
Arch Surg ; 113(5): 618-20, 1978 May.
Article in English | MEDLINE | ID: mdl-25642

ABSTRACT

Preoperative preparation of rats with lactulose, 2.5 ml/kg of a 52.5% w/w solution, for two days resulted in increased bursting pressure and bursting wall tension of low colonic anastomoses three days postoperatively when compared with unprepared controls (85.8, viz, 36.1 mm Hg and 0.55, viz, 0.19 dynes/cm X 10(-5). After seven days, there was no appreciable difference in the rats with colonic acidification and in the controls.


Subject(s)
Cicatrix/drug therapy , Colostomy , Disaccharides/therapeutic use , Lactulose/therapeutic use , Surgical Wound Dehiscence/drug therapy , Animals , Drug Evaluation , Hydrogen-Ion Concentration , Pressure , Rats , Time Factors
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