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1.
Veg Hist Archaeobot ; 33(4): 475-487, 2024.
Article in English | MEDLINE | ID: mdl-38803354

ABSTRACT

The functional ecology of arable weeds provides a way of comparing present-day and past farming regimes. This paper presents the R package WeedEco, an open-source resource which allows users to compare their archaeobotanical dataset against three previously published arable weed models to understand fertility, disturbance or a combination of both. The package provides functions for data organisation, classification and visualisation, allowing users to enter raw archaeobotanical data, obtain trait values from the functional trait dataset, conduct discriminant analysis and plot the results against the relevant present-day model. Using data from the early medieval site of Stafford in the UK, the paper provides a detailed example of the use of the package, demonstrating its different functions, as well as how the results can be interpreted. Supplementary Information: The online version contains supplementary material available at 10.1007/s00334-023-00964-8.

2.
A A Pract ; 18(3): e01762, 2024 Mar 01.
Article in English | MEDLINE | ID: mdl-38498670

ABSTRACT

Semaglutide, a glucagon-like peptide-1 (GLP-1) analog, has various effects on the gastrointestinal tract. In patients undergoing anesthesia delayed gastric emptying time can have sequelae if not identified preoperatively. Modalities include thorough history regarding the last dose administration of a GLP-1 analog and ultrasound of gastric contents before induction of anesthesia. We present a case in which gastric ultrasound identified a patient at increased risk for aspiration on induction and allowed for appropriate alterations in the anesthetic plan.


Subject(s)
Glucagon-Like Peptide 1 , Glucagon-Like Peptides , Point-of-Care Systems , Humans , Gastrointestinal Tract , Point-of-Care Testing
3.
Nat Biotechnol ; 42(2): 170-172, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38361065
4.
Nat Biotechnol ; 42(2): 167-169, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38361057
9.
Nat Biotechnol ; 41(11): 1501-1503, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37950013
10.
Best Pract Res Clin Anaesthesiol ; 37(3): 357-372, 2023 Sep.
Article in English | MEDLINE | ID: mdl-37938082

ABSTRACT

Patient selection is important for ambulatory surgical practices. Proper patient selection for ambulatory practices will optimize resources and lead to increased patient and provider satisfaction. As the number and complexity of procedures in ambulatory surgical centers increase, it is important to ensure that patients are best cared for in facilities that can provide appropriate levels of care. This review addresses the multiple variables and resources that should be considered when selecting patients for anesthesia in ambulatory centers and offices.


Subject(s)
Anesthesia , Anesthesiology , Humans , Ambulatory Surgical Procedures , Patient Selection
11.
ArXiv ; 2023 Oct 09.
Article in English | MEDLINE | ID: mdl-37873019

ABSTRACT

Experimental observations suggest that the force output of the skeletal muscle tissue can be correlated to the intra-muscular pressure generated by the muscle belly. However, pressure often proves difficult to measure through in-vivo tests. Simulations on the other hand, offer a tool to model muscle contractions and analyze the relationship between muscle force generation and deformations as well as pressure outputs, enabling us to gain insight into correlations among experimentally measurable quantities such as principal and volumetric strains, and the force output. In this work, a correlation study is performed using Pearson's and Spearman's correlation coefficients on the force output of the skeletal muscle, the principal and volumetric strains experienced by the muscle and the pressure developed within the muscle belly as the muscle tissue undergoes isometric contractions due to varying activation profiles. The study reveals strong correlations between force output and the strains at all locations of the belly, irrespective of the type of activation profile used. This observation enables estimation on the contribution of various muscle groups to the total force by the experimentally measurable principal and volumetric strains in the muscle belly. It is also observed that pressure does not correlate well with force output due to stress relaxation near the boundary of muscle belly.

12.
Nat Biotechnol ; 41(8): 1041-1043, 2023 08.
Article in English | MEDLINE | ID: mdl-37500917
13.
Nat Biotechnol ; 41(8): 1044-1046, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37500918
14.
Nat Biotechnol ; 41(5): 591-593, 2023 05.
Article in English | MEDLINE | ID: mdl-37193837

Subject(s)
Biodiversity , Geography
15.
Nat Biotechnol ; 41(5): 594-596, 2023 05.
Article in English | MEDLINE | ID: mdl-37193838
16.
Nat Biotechnol ; 41(2): 167-169, 2023 Feb.
Article in English | MEDLINE | ID: mdl-36732480
17.
Nat Biotechnol ; 41(2): 170-173, 2023 Feb.
Article in English | MEDLINE | ID: mdl-36732481
18.
A A Pract ; 17(2): e01663, 2023 Feb 01.
Article in English | MEDLINE | ID: mdl-36779890

ABSTRACT

Pulmonary artery aneurysms are frequently managed with endovascular embolization. Rare but serious complications of coil embolization are erosion and migration of the coils into the adjacent airways, posing a risk for massive hemoptysis. We report the case of a medically complex patient with a left main pulmonary artery aneurysm treated with coil embolization who ultimately experienced transbronchial migration and expectoration of the coil. We discuss the challenging anesthetic and surgical management of these serious complications, including the use of an endovascular plug to occlude the erosion site and distal airways.


Subject(s)
Embolization, Therapeutic , Pulmonary Artery , Humans , Blood Vessel Prosthesis
19.
Acad Med ; 98(4): 497-504, 2023 04 01.
Article in English | MEDLINE | ID: mdl-36477379

ABSTRACT

PURPOSE: Faculty feedback on trainees is critical to guiding trainee progress in a competency-based medical education framework. The authors aimed to develop and evaluate a Natural Language Processing (NLP) algorithm that automatically categorizes narrative feedback into corresponding Accreditation Council for Graduate Medical Education Milestone 2.0 subcompetencies. METHOD: Ten academic anesthesiologists analyzed 5,935 narrative evaluations on anesthesiology trainees at 4 graduate medical education (GME) programs between July 1, 2019, and June 30, 2021. Each sentence (n = 25,714) was labeled with the Milestone 2.0 subcompetency that best captured its content or was labeled as demographic or not useful. Inter-rater agreement was assessed by Fleiss' Kappa. The authors trained an NLP model to predict feedback subcompetencies using data from 3 sites and evaluated its performance at a fourth site. Performance metrics included area under the receiver operating characteristic curve (AUC), positive predictive value, sensitivity, F1, and calibration curves. The model was implemented at 1 site in a self-assessment exercise. RESULTS: Fleiss' Kappa for subcompetency agreement was moderate (0.44). Model performance was good for professionalism, interpersonal and communication skills, and practice-based learning and improvement (AUC 0.79, 0.79, and 0.75, respectively). Subcompetencies within medical knowledge and patient care ranged from fair to excellent (AUC 0.66-0.84 and 0.63-0.88, respectively). Performance for systems-based practice was poor (AUC 0.59). Performances for demographic and not useful categories were excellent (AUC 0.87 for both). In approximately 1 minute, the model interpreted several hundred evaluations and produced individual trainee reports with organized feedback to guide a self-assessment exercise. The model was built into a web-based application. CONCLUSIONS: The authors developed an NLP model that recognized the feedback language of anesthesiologists across multiple GME programs. The model was operationalized in a self-assessment exercise. It is a powerful tool which rapidly organizes large amounts of narrative feedback.


Subject(s)
Internship and Residency , Humans , Artificial Intelligence , Clinical Competence , Education, Medical, Graduate , Feedback
20.
Nat Biotechnol ; 40(6): 821-828, 2022 06.
Article in English | MEDLINE | ID: mdl-35650288

Subject(s)
Biotechnology
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