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1.
Anat Histol Embryol ; 44(2): 107-17, 2015 Apr.
Article in English | MEDLINE | ID: mdl-24712373

ABSTRACT

Current methods of diagnosis of respiratory diseases in swine are invasive, time-consuming and expensive. Infrared thermography (IRT) of the thorax might provide a new method of high specificity to select swine affected with lung alterations for further diagnostics. In this study, layer thickness of different tissues was determined in frozen thorax slices (FTS) by computed tomography (CT) and then related to skin temperatures measured by IRT in healthy pigs. The aim was to determine appropriate regions of interest (ROI) for evaluation of IRT images. Organ layer thicknesses measured in CT images correspond to those measured in FTS. Temperature differences between lung ROIs and abdomen ROIs were positively correlated with lung layer thickness at certain localizations, and negatively correlated with the thickness of the thorax wall and of inner organ layers. Reference values of differences between skin temperatures were established for two ROIs on the thorax with potential practical use for lung health status determination. Respective ROIs were located on vertical lines crossing the 7th (right) and the 10th (left) thoracic vertebrae. The presence of ribs affected skin temperature significantly.


Subject(s)
Lung Diseases/veterinary , Skin Temperature , Swine Diseases/diagnosis , Swine/anatomy & histology , Swine/physiology , Thermography/veterinary , Thorax/anatomy & histology , Thorax/physiology , Abdomen/anatomy & histology , Abdomen/physiology , Anatomy, Cross-Sectional , Animals , Infrared Rays , Lung/anatomy & histology , Lung/diagnostic imaging , Lung/physiology , Lung Diseases/diagnosis , Male , Radiography, Thoracic/veterinary , Reference Values , Thermography/methods , Tomography, X-Ray Computed/methods , Tomography, X-Ray Computed/veterinary
2.
Dtsch Tierarztl Wochenschr ; 115(7): 260-4, 2008 Jul.
Article in German | MEDLINE | ID: mdl-18672736

ABSTRACT

Here we present the work of the multidisciplinary consortium IRAS (Development of Genetic Markers for Immune Defence and Resistance in the Porcine Respiratory Tract) which includes different commercial and research institutions and was formed as a response to the call "Functional Genome Analysis in the Animal Organism (FUGATO)" by the German Ministry of Education and Research. IRAS started work in the fall of 2005 and--using the experimental infection of pigs with Actinobacillus pleuropneumoniae as model pathogen--aims at i) characterizing the course of infection by clinical as well as advanced laboratory tools (phenotypic-genetic approach) and ii) defining the diversity and distribution of allels known to be associated with immune defence in mouse and man (homolog-genetic approach). The intention is to identify genetic markers for increased resistance to infection thereby providing additional tools for the estimation of breeding values to the pig industry.


Subject(s)
Actinobacillus Infections/veterinary , Actinobacillus pleuropneumoniae , Immunity, Innate/genetics , Respiratory Tract Infections/veterinary , Swine Diseases/immunology , Actinobacillus Infections/genetics , Actinobacillus Infections/immunology , Actinobacillus Infections/pathology , Animals , Breeding , Genetic Markers/immunology , Genotype , Immunity, Innate/immunology , Lung/microbiology , Lung/pathology , Respiratory Tract Infections/genetics , Respiratory Tract Infections/immunology , Respiratory Tract Infections/pathology , Severity of Illness Index , Swine , Swine Diseases/genetics , Swine Diseases/pathology , Time Factors
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