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1.
Cytokine secretion is impaired in women with diabetes mellitus.
Geerlings, S E; Brouwer, E C; van Kessel, K P; Gaastra, W; Hoepelman, A M.
Adv Exp Med Biol ; 485: 255-62, 2000.
Article in English | MEDLINE | ID: mdl-11109114

Subject(s)
Bacteriuria/immunology , Cytokines/blood , Cytokines/urine , Diabetes Mellitus/immunology , Lymphocytes/immunology , Adolescent , Adult , Aged , Cells, Cultured , Cytokines/biosynthesis , Diabetes Mellitus/blood , Diabetes Mellitus/urine , Diabetes Mellitus, Type 1/immunology , Diabetes Mellitus, Type 1/urine , Diabetes Mellitus, Type 2/immunology , Diabetes Mellitus, Type 2/urine , Female , Glycosuria , Humans , Interleukin-6/urine , Interleukin-8/urine , Leukocytes , Lipopolysaccharides/pharmacology , Lymphocytes/drug effects , Middle Aged , Reference Values , Salmonella , Tumor Necrosis Factor-alpha/urine , Urine/cytology
2.
Virulence factors of Escherichia coli isolated from urine of diabetic women with asymptomatic bacteriuria.
Geerlings, S E; Brouwer, E C; Gaastra, W; Hoepelman, A M.
Adv Exp Med Biol ; 485: 249-54, 2000.
Article in English | MEDLINE | ID: mdl-11109113

Subject(s)
Bacteriuria/microbiology , Diabetes Mellitus/urine , Escherichia coli/pathogenicity , Adolescent , Adult , Aged , Diabetes Mellitus, Type 1/urine , Diabetes Mellitus, Type 2/urine , Escherichia coli/classification , Escherichia coli/isolation & purification , Female , Hemagglutination Tests , Humans , Middle Aged , Polymerase Chain Reaction , Serotyping
3.
Asymptomatic bacteriuria can be considered a diabetic complication in women with diabetes mellitus.
Geerlings, S E; Stolk, R P; Camps, M J; Netten, P M; Hoekstra, J B; Bouter, P K; Braveboer, B; Collet, T J; Jansz, A R; Hoepelman, A M.
Adv Exp Med Biol ; 485: 309-14, 2000.
Article in English | MEDLINE | ID: mdl-11109121

Subject(s)
Bacteriuria/epidemiology , Diabetes Complications , Urine/microbiology , Adolescent , Adult , Aged , Albuminuria , Diabetes Mellitus/microbiology , Diabetes Mellitus, Type 1/complications , Diabetes Mellitus, Type 2/complications , Female , Humans , Middle Aged , Risk Factors
4.
Streptococcus pneumoniae induces secretion of vascular endothelial growth factor by human neutrophils.
van Der Flier, M; Coenjaerts, F; Kimpen, J L; Hoepelman, A M; Geelen, S P.
Infect Immun ; 68(8): 4792-4, 2000 Aug.
Article in English | MEDLINE | ID: mdl-10899891

ABSTRACT

Infection by pneumococci causes an acute inflammatory response associated with neutrophil influx, increased vascular permeability, and edema. Vascular endothelial growth factor (VEGF) is one of the most potent regulators of endothelial permeability. In vitro stimulation of neutrophils showed that pneumococci and purified pneumococcal cell wall induce VEGF secretion, independent of the presence of pneumolysin or polysaccharide capsule. The results of this study indicate VEGF is secreted in pneumococcal disease, suggesting a role as a mediator of increased vascular permeability.


Subject(s)
Endothelial Growth Factors/metabolism , Lymphokines/metabolism , Neutrophils/immunology , Streptococcus pneumoniae/immunology , Bacterial Capsules/immunology , Capillary Permeability , Endothelium, Vascular , Humans , Vascular Endothelial Growth Factor A , Vascular Endothelial Growth Factors
5.
Delayed-type hypersensitivity skin testing in patients with HIV infection.
Borleffs, J C; Vrehen, H M; Bosboom-Kalsbeek, K C; Hoepelman, A M; Schuurman, H J; Gmelig-Meyling, F H.
AIDS ; 5(1): 110-2, 1991 Jan.
Article in English | MEDLINE | ID: mdl-2059351

Subject(s)
HIV Infections/immunology , Hypersensitivity, Delayed/immunology , HIV Infections/drug therapy , Humans , Leukocyte Count , Skin Tests , T-Lymphocyte Subsets , Zidovudine/therapeutic use
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