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1.
Sci Rep ; 10(1): 5690, 2020 03 30.
Article in English | MEDLINE | ID: mdl-32231222

ABSTRACT

To optimize the placement of iliosacral screws in osteoporotic bone it is essential to know where to find the best purchase. The aim of this study was to determine and visualize the distribution of bone mass in the posterior pelvic ring by using a color-coded thermal map, to differentiate the bone distribution patterns in normal pelvises and in pelvises with impaired bone density and to identify zones in S1 and S2 with particularly good bone quality, in both healthy and osteoporotic pelvises. A total of 324 pelvises were included. The bone density of the posterior pelvic ring, the fifth lumbar vertebral body (L5) and screw corridors S1 and S2 were visualized. Each individual pelvis was measured with a 3D automated program. Two groups were selected - patients with mean bone density in L5 of ≤100 HU (group 1, n = 52) and those with mean bone density >100 HU (group 2, n = 272). Color-coded thermal maps are presented of the bone density distribution in the pelvises. Bone density in L5 correlated significantly with S1 and S2; bone density was significantly higher in the S1 than in the S2 corridor (p < 0.001). Bone was denser in the posterior and upper parts of the S1 body. Bone density was significantly lower in group 2 than in group 1 (p < 0.001). The color-coded "thermal" maps of bone mass distribution can help surgeons to decide where sacroiliac screws are likely to find optimal purchase.


Subject(s)
Bone Density , Bone Screws , Pelvic Bones/anatomy & histology , Sacrum , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Imaging, Three-Dimensional , Lumbar Vertebrae/anatomy & histology , Lumbar Vertebrae/diagnostic imaging , Male , Middle Aged , Osteoporotic Fractures/pathology , Osteoporotic Fractures/surgery , Pelvic Bones/diagnostic imaging , Pelvic Bones/injuries , Sacrum/anatomy & histology , Sacrum/diagnostic imaging , Tomography, X-Ray Computed , Young Adult
2.
J Orthop Res ; 37(7): 1508-1517, 2019 07.
Article in English | MEDLINE | ID: mdl-30977547

ABSTRACT

This study evaluated the implementation and effectiveness of an iterative process aimed to quantify and enhance the anatomical fit of an osteosynthesis plate design for the fifth metacarpal bone regarding a defined shape-based acceptance criterion (SAC) while complying with basic clinical requirements and engineering limitations. The process was based on employing virtual tools (a database of individual three-dimensional bone models, statistical analysis of the bone geometry, and proprietary software tools) to evaluate conformity between plate designs and bone shape. The conformity was quantified by the mean distance between plate and bone (MBP). The enhancement was completed when the median MBP of the population was below the SAC threshold. This was fulfilled by the third plate design (two enhancement iterations). The intentionally abstract enhancement process may serve as a guideline for development of plate designs for other indications. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:1508-1517, 2019.


Subject(s)
Bone Plates , Fracture Fixation, Internal/instrumentation , Prosthesis Design/methods , Humans
3.
PLoS One ; 13(10): e0204961, 2018.
Article in English | MEDLINE | ID: mdl-30300421

ABSTRACT

INTRODUCTION: For optimal treatment of femoral fractures, it is essential to understand the anatomical antecurvation of the human femur. Recent clinical studies have highlighted the problem of distal anterior encroachment or even perforation of the nail tip. The aim of this study was to accurately describe the femoral antecurvation in a large cohort. Another objective was to identify the most important influences on femoral antecurvation, such as age, femur length, gender and ethnicity. METHODS: A three dimensional modelling and analytical technology was applied for the analysis of 1,232 femurs. Individual femoral antecurvation was precisely computed to determine whether gender, femur length, age, ethnicity or body mass index influence the radius of curvature (ROC). RESULTS: The calculated mean ROC for all femurs was 943 mm. The lowest ROC of 826 mm was found in female Asian femurs. A regression analysis demonstrated that age and femur length could predict the variability of the curvature, with femoral length as most powerful predictor. A matched pair subgroup analysis between Asians and Caucasians could not show any significant differences of ROC values. CONCLUSIONS: The mean radius of the femoral antecurvation may be smaller than previously reported revealing a significant mismatch between the actual individual anatomy and existing implants. In opposite to existing literature, this study suggests, that antecurvation differences between various ethnicities may exclusively be attributed to differences in femoral length and age. The findings of this study may be found helpful in the development of novel designs for intra- and extramedullary implants.


Subject(s)
Femur/physiology , Tomography, X-Ray Computed , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Asian People , Body Mass Index , Femur/diagnostic imaging , Humans , Imaging, Three-Dimensional , Male , Middle Aged , Sex Factors , White People , Young Adult
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