Subject(s)
Abscess/etiology , Gonorrhea/complications , Skin Diseases/etiology , Adult , Aged , Female , HumansABSTRACT
The acquired immunodeficiency syndrome (AIDS) is manifested by severe immunologic (predominantly T-lymphocyte) abnormalities and opportunistic infections. Central nervous system (CNS) infections are frequent. Pathogens causing CNS infections in AIDS patients include parasites, fungi, and viruses and are similar to those reported in other states of impaired cell mediated immunity (CMI). A case of relapsing, bacteremic Klebsiella pneumoniae meningitis in an AIDS patient is presented.
Subject(s)
Acquired Immunodeficiency Syndrome/complications , Klebsiella Infections/immunology , Meningitis/etiology , Sepsis/etiology , Adult , Anti-Bacterial Agents/therapeutic use , Antibodies, Bacterial/immunology , Drug Therapy, Combination , Humans , Klebsiella Infections/drug therapy , Klebsiella pneumoniae/immunology , Male , RecurrenceABSTRACT
Malignant external otitis (MEO) is a progressive necrotizing infection which spreads to the skull base. The causative organism is usually Pseudomonas aeruginosa and 90% of the patients are diabetic. The infection gains access to the skull base at the temporal bone. Cranial nerve involvement is common. We present a case of malignant external otitis causing blindness due to optic neuritis. Progressive vascular involvement along the skull base is the pathogenic mechanism that best explains spread from the temporal bone to the orbital apex.
