Electrophysiological measurements and analysis of nociception in human infants.

Pain is an unpleasant sensory and emotional experience. Since infants cannot verbally report their experiences, current methods of pain assessment are based on behavioural and physiological body reactions, such as crying, body movements or changes in facial expression. While these measures demonstrate that infants mount a response following noxious stimulation, they are limited: they are based on activation of subcortical somatic and autonomic motor pathways that may not be reliably linked to central sensory processing in the brain. Knowledge of how the central nervous system responds to noxious events could provide an insight to how nociceptive information and pain is processed in newborns. The heel lancing procedure used to extract blood from hospitalised infants offers a unique opportunity to study pain in infancy. In this video we describe how electroencephalography (EEG) and electromyography (EMG) time-locked to this procedure can be used to investigate nociceptive activity in the brain and spinal cord. This integrative approach to the measurement of infant pain has the potential to pave the way for an effective and sensitive clinical measurement tool.

Of needles and skinned knees: children's coping with medical procedures and minor injuries for self and other.

Children participated in four role-plays designed to assess what the children themselves would do and what they would suggest a friend should do when encountering a medical procedure and a minor injury. Open-ended responses were coded into an empirically derived continuum suggested by past research. Similar responses were given to cope with medical procedures and injuries. However, children suggested more reactive coping strategies (e.g., cry, pull away) for themselves and more proactive responses (e.g., think of something fun, take deep breaths) for friends. This finding questions the assumption that children choose the most effective coping strategy in their repertoire when they themselves confront an aversive stimulus, suggesting that preparation for invasive procedures should include motivational components.