Efectividad de un extracto de placentahumana con calcio (Melagenina Plus) en eltratamiento del vitíligo / Effectiveness of human placental extract with calcium (melagenina plus) for the treatment of vitiligo

Los extractos alcohólicos de placenta humana han demostrado poseer una actividad en la melanogénesis y sobre en la proliferación de los melanocitos.Tales extractos producen un incremento en la densidad de los melanocitos así como de los gránulos de melanina cuando son aplicados tópicamentesobre las orejas y colas de ratones negros.Objetivo: Evaluar la acción de un extracto alcohólico de placenta humana con calcio (Melagenina Plus®) en el tratamiento del Vitiligo, por ser esta unaenfermedad en la que se pierden los melanocitos y por ende el pigmento melánico.Se realizó un estudio retrospectivo con 300 pacientes de vitiligo cubanos que fueron seleccionados por haber realizado de forma correcta la aplicacióndel extracto alcohólico de placenta humana con calcio sobre sus áreas despigmentadas. La selección se realizó con pacientes que se incorporaron altratamiento con Melagenina Plus en los Servicios Clínicos del Centro de Histoterapia Placentaria entre los años 1998 hasta el 2003.Al final del estudio 231 pacientes mostraron repigmentación completa o notable, 28 repigmentación parcial, 24 ninguna repigmentación y 17 nuevaslesiones. Nuestros resultados demuestran que el extracto alcohólico de placenta con adición de calcio puede ser un eficaz e inocuo en el tratamientodel Vitiligo (AU)

Human placental alcohol extract have been successfully used on melanogenesis and melanocyte proliferation. Such extracts cause an increase in thenumber of melanocytes and melanin granules when applied topically on the ears and tails of black mice.Objetives: Assessment of the effectiveness of a human placental alcohol extract with calcium (Melagenina Plus®) for the treatment of vitiligo, sincethis disease is characterized by melanocyte loss and consequently of melanine pigment.A retrospective study was carried out with 300 cuban vitiligo patients which were chosen because of their correct application on their depigmentedareas of the human placental alcohol extract with calcium. Patients selection was made among those involved in the treatment with Melagenina Plusfrom the Clinical Service of the Placental Histotherapy Center since 1998 to 2003.At the end of the study, 231 patients showed total or marked repigmentation, 28 moderate repigmentation, 24 no repigmentation and 17 newlesions. Results demonstrate that placental alcohol extracts with calcium added can be very effective and innocuous for the vitiligo treatment (AU)

[Effect of physico-chemical factors of the soil on the Oribatid population]. / Influencia de factores físico-químicos del suelo sobre poblaciones de Oribátidos.

Orbatid populations present in the ground of four randomly selected patches of land for calf farming underwent ecology during four months. The statistical analysis of results disclosed a highly significative decrease of the population in one out of such patches of land. The physicochemical analysis of earth samples from each patch of land permitted the explanation for the phenomenon on the basis of an increased calcium concentration in the least populated patch of land.

[1st report of an intermediary host of Moniezia sp in Cuba]. / Primer informe de un hospedero intermediario de Moniezia sp. para Cuba.

The determination of an oribatid belonging to the Scheloribates genus as an intermediary host of the Moniezia sp. helminth is reported for the first time in Cuba. Photographs and measurements taken during the infecting larval state of Moniezia (cisticercoid) found are included, such as it is observed because of transparency in the interior of acarus and drew out from the Latter for its better identification.

[Determination of cholinesterase activity in Fasciola hepatica homogenates]. / Determinación de actividad colinesterásica en homogeneizados de Fasciola hepatica.

The cholinesterase activity in Fasciola hepatica homogenates was studied through biological techniques. Results depict that the contractile stimulating action of a constant acetylcholine dose on the isolated rat duodenum is withdrawn when the agent is previously incubated at 37 degrees C during 30 minutes with different dilutions (20%, 40% and 80%) of Fasciola hepatica homogenates. The action is recovered when an anticholinesterase, as neostigmine is previously added to the homogenate. Since these effects are similar to those obtained when different dilutions of human blood serum with a high content of cholinesterase are led to act upon the acetylcholine dose, it is concluded that the acetylcholine inactivation induced by Fasciola hepatica homogenates results from the existence of such enzyme within this parasite.