1.
Cytogenet Cell Genet
; 72(4): 306-9, 1996.
Article
in English
| MEDLINE
| ID: mdl-8641136
ABSTRACT
The Wilms' tumor suppressor 1 gene (WT1) encodes a zinc finger transcription factor critical for normal urogenital development. We have previously isolated a DNA fragment, +P5 (D1S3309E), to which all WT1 protein isoforms bind. Using PCR of a human x rodent somatic cell hybrid mapping panel, together with two-color fluorescence in situ hybridisation of +P5-containing cosmids and previously localised human chromosome 1q cosmids, we have mapped the +P5 fragment to chromosome 1q21-->q22.
Subject(s)
Chromosomes, Human, Pair 1/genetics , DNA-Binding Proteins/genetics , DNA/genetics , DNA/metabolism , Genes, Wilms Tumor , Transcription Factors/genetics , Zinc Fingers/genetics , Animals , Base Sequence , Binding Sites/genetics , Chromosome Mapping , Chromosomes, Human, Pair 1/ultrastructure , Cosmids , DNA Primers/genetics , Humans , Hybrid Cells , In Situ Hybridization, Fluorescence , Molecular Sequence Data , Polymerase Chain Reaction , WT1 Proteins
2.
J Iowa Med Soc
; 70(2): 57-60, 1980 Feb.
Article
in English
| MEDLINE
| ID: mdl-7354221
Subject(s)
Metrizamide , Myelography/methods , Electromyography , Humans , Metrizamide/adverse effects , Spinal Puncture
3.
J Iowa Med Soc
; 67(1): 14-6, 1977 Jan.
Article
in English
| MEDLINE
| ID: mdl-833453
