1.
Chem Commun (Camb)
; 51(82): 15180-3, 2015 Oct 21.
Article
in English
| MEDLINE
| ID: mdl-26327521
ABSTRACT
The feasibility of a neighboring boronic acid-facilitated facile condensation of an aldehyde is described. This reaction is bio-orthogonal, complete at room temperature within minutes, and suitable for bioconjugation chemistry. The boronic acid group serves the dual purpose of catalyzing the condensation reaction and being a handle for secondary functionalization.