ABSTRACT
Due to the inconsistent fluctuation of blood supply for transfusion, much attention has been paid to the development of artificial blood using other animals. Although mini-pigs are candidate animals, contamination of mini-pig T cells in artificial blood may cause a major safety concern. Therefore, it is important to analyze the cross-reactivity of IL-7, the major survival factor for T lymphocytes, between human, mouse, and mini-pig. Thus, we compared the protein sequences of IL-7 and found that porcine IL-7 was evolutionarily different from human IL-7. We also observed that when porcine T cells were cultured with either human or mouse IL-7, these cells did not increase the survival or proliferation compared to negative controls. These results suggest that porcine T cells do not recognize human or mouse IL-7 as their survival factor.
ABSTRACT
Metallic organic frameworks (MOFs) with mixed metals has attracted attention as electrochemical energy storage material because it has high specific surface area, synergy of two metals, and a new crystal structure different from that of conventional MOF. In this study, we synthesized MOFs, including nickel and zinc, by hydrothermal method at a time. We investigated the effect of two metal ratios on the capacitive behavior. Through the structure and morphology analysis, it was found that Ni-Zn-MOF forms a completely different crystal structure from MOF using one metal, and found that it is a porous material. As a result of electrochemical measurements with cyclic voltammetry (CV) and galvanostatic charge-discharge (GCD), the specific capacitance of Ni-Zn-MOF 2:1 with a nickel to zinc ratio of 2:1 was 616 F g-1 at a current density was 1 A g-1.
