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1.
Sci Rep ; 10(1): 14454, 2020 09 02.
Article in English | MEDLINE | ID: mdl-32879338

ABSTRACT

The purpose of this study is to evaluate the changes in the palatal alveolar bone thickness and find the factors related to the resorption of the palatal alveolar bone caused by tooth movement after the maxillary incisors were retracted and intruded during orthodontic treatment. The study group comprised of 33 skeletal Class II malocclusion patients who underwent extraction for orthodontic treatment. Palatal alveolar bone thickness changes and resorption factors were identified and analyzed. The changes of maxillary central incisors and palatal alveolar bone thickness were measured, and the corresponding sample t test was performed using SPSS (IBM SPSS version 22). The amount of palatal alveolar bone resorption was measured and various parameters were analyzed to determine which factors affected it. Correlation analysis adopting the amount of palatal alveolar bone resorption as a dependent variable demonstrated that the SNB, mandibular plane angle, and the inclination of the maxillary central incisor were significantly correlated with before treatment. On the other hand, mandibular plane angle, angle of convexity, the inclination of the upper incisor, and the occlusal plane (UOP, POP) were significantly correlated with post-treatment. In addition, the variables related to palatal contour (PP to PAS, SN to PAS, palatal surface angle) and occlusal planes (UOP/POP) were significantly correlated with the difference in palatal bone resorption. During initial diagnosis, high angle class II with normal upper incisor inclination can be signs of high-risk factors. In addition, maintaining the occlusal plane during treatment helps to prevent palatal bone loss.


Subject(s)
Alveolar Process/diagnostic imaging , Incisor/growth & development , Palate/growth & development , Tooth Movement Techniques , Adult , Alveolar Process/growth & development , Cephalometry , Cone-Beam Computed Tomography , Female , Humans , Incisor/diagnostic imaging , Male , Maxilla/diagnostic imaging , Maxilla/growth & development , Palate/diagnostic imaging , Young Adult
2.
Prog Orthod ; 20(1): 47, 2019 Dec 23.
Article in English | MEDLINE | ID: mdl-31867679

ABSTRACT

BACKGROUND: Maxillary incisor protrusion is a prevalent dental deformity and is often treated by upper incisor intrusion and retraction. The mechanical loading triggers the resorption and apposition of the bone. Alveolar bone remodeling is expected to follow orthodontic tooth movement in a one-to-one relationship. However, in many cases, the outcomes are different. Alveolar bone might still remain thick causing lip protrusion and other aesthetic problems after treatment. Additional corrective procedures such as alveoloplasty. On the other hand, if the labial bone becomes too thin, periodontal problems like gingival recession might occur. The unpredictability of the treatment result and the risk of requiring corrective procedures pose significant challenges to both the providers and patients. The aim of this study is to determine factors that can help to predict the alveolar bone reaction before maxillary incisor intrusion and retraction. METHODS: The cohort included 34 female patients (mean age 25.8 years) who were diagnosed with skeletal class II malocclusion with upper incisor protrusion. These patients underwent extraction and orthodontic treatment with upper incisor intrusion and retraction. Lateral cephalograms at pre-treatment and post-treatment were taken. Linear and angular measurements were analyzed to evaluate the alveolar bone changes based on initial conditions. RESULTS: The study found that the relative change, calculated as change in alveolar bone thickness after treatment divided by the initial alveolar thickness, was inversely correlated with the initial thickness. There was a significant increase of labial alveolar bone thickness at 9-mm apical from cementoenamel junction (B3) (P < 0.05) but no statistically significant change in the thickness at other levels. In addition, the change in angulation between the incisor and alveolar bone was inversely correlated with several initial angulations: between the initial palatal plane and upper incisor angle, between the initial palatal plane and upper incisor labial surface angle, and between the initial palatal plane and bone labial surface angle. On the other hand, the change in labial bone thickness was neither significantly correlated with the initial thickness nor significantly correlated to the amount of retraction. CONCLUSION: The unpredictability of alveolar bone remodeling after upper incisor intrusion and retraction poses significant challenges to treatment planning and patient experience. The study showed that the initial angulation between the incisor and alveolar bone is correlated with the change in angulation after treatment, the initial thickness of the alveolar bone was correlated with the relative change of the alveolar bone thickness (defined as change in thickness after treatment divided by its initial thickness), and the amount of intrusion was correlated with the alveolar bone thickness change at 9-mm apical from the cementoenamel junction after treatment. The results of the present study also revealed that the change in labial alveolar bone thickness was neither significantly correlated with the initial thickness nor significantly correlated to the amount of retraction.


Subject(s)
Esthetics, Dental , Incisor , Adult , Bone Remodeling , Cephalometry , Female , Humans , Maxilla , Tooth Movement Techniques
3.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-177377

ABSTRACT

BACKGROUND: The diagnosis of bromhidrosis is a clinical one, but the definition of "normal" odor is a poorly defined term. In the Asian population, the presence of even a faint odor is considered diagnostic. For the more exact evaluation, it is vital to study more findings associated with bromhidrosis. Recently, several studies have suggested possibility that the activity of sebaceous gland may be increased in patients with bromhidrosis. OBJECTIVE: The aim of this study was to compare the differences of the seborrheic phenotypes and the measured serum level of facial skin surface between patients with bromhidrosis and the normal population. METHODS: Twenty patients who were diagnosed with bromhidrosis by nose smell test and age-matched twenty from the normal population were evaluated with regard to the presence of seborrheic skin phenotypes suggested by Ely. We also measured sebum level of facial skin by Sebumeter(R). RESULTS: The presence of some seborrheic skin phenotypes such as telangiectasia and square palm were increased significantly in the patients. In addition, objectively measured sebum of facial skin surface was relatively increased in the patients. CONCLUSION: We concluded that there is an association between apocrine bromhidrosis and seborrheic skin phenotype.


Subject(s)
Humans , Asian People , Diagnosis , Nose , Odorants , Phenotype , Sebaceous Glands , Sebum , Skin , Smell , Telangiectasis
4.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-180462

ABSTRACT

Plasma cell cheilitis is an idiopathic, benign, inflammatory mucosal condition characterized histologically by a dense band-like infiltrate of plasma cells in the upper dermis of the mucosa. In addition to the lips, the disease can affect the penis, vulva, buccal mucosa, palate, gingiva, tongue, epiglottis, and larynx. Plasma cell cheilitis of the lip appears as a circumscribed, flat to slightly elevated, eroded area, usually on the lower lip of an elderly person. We report a 70-year-old man who had a well-demarcated, erythematous, erosive lesion on his lower lip for 1 year. A biopsy specimen showed an upper dermal infiltrate that consisted mainly of plasma cells. Oral griseofulvin, 500mg/day, was begun, and 8 weeks later the lesion showed marked improvement.


Subject(s)
Aged , Humans , Male , Biopsy , Cheilitis , Cytochrome P-450 CYP1A1 , Dermis , Epiglottis , Gingiva , Griseofulvin , Larynx , Lip , Mouth Mucosa , Mucous Membrane , Palate , Penis , Plasma Cells , Plasma , Tongue , Vulva
5.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-21204

ABSTRACT

Docetaxel is a new taxoid antineoplastic drug widely used for advanced breast cancer , ovarian cancer . Skin and nail toxicity are one of the more frequent nonhematologic adverse reactions. Especially, nail changes include dark pigmentation, subungual hemorrahage, acute paronychia, onycholysis, Beau s line etc. We have observed a striking example of multiple Beau s lines from all fingernails and toenails in a man receiving a docetaxel infusion for treatment of metastatic cancer with unknown-origin.


Subject(s)
Breast Neoplasms , Nails , Onycholysis , Ovarian Neoplasms , Paronychia , Pigmentation , Skin , Strikes, Employee
6.
Korean Journal of Dermatology ; : 1401-1403, 2001.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-182147

ABSTRACT

Follicular hamartoma is a rare, benign adnexal tumor with varieties of clinical diversity. But, Histological feature is characterized by a proliferation of immature hair follicle in the dermis with multifocal islands and thickened perifollicular sheath. Pili multigemini is also a rare, developmental anomaly of hair growth with multiple hairs from two or more matrices and papillae in a single pilosebaceous unit. Its prevalence and pathogenesis are unknown. We describe herein a rare case of localized follicular hamartoma with pili multigemini suggesting the possibility of association on pathogenesis between them.


Subject(s)
Dermis , Hair , Hair Follicle , Hamartoma , Islands , Prevalence
7.
Korean Journal of Dermatology ; : 1310-1312, 2001.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-48818

ABSTRACT

Eccrine porocarcinoma is a very rare, locally aggressive, potentially fatal tumor arising from the intraepidermal ductal portion of the eccrine sweat gland. It develops either spontaneously or from a long standing benign eccrine poroma. It usually affects older persons and is located most commonly on the lower extremities. It is a slow growing tumor and clinically resembles other skin cancers. We report a case of eccrine porocarcinoma in a 57-year-od man. In this case, the tumor was located on the volar aspect of the right thumb, showing verrucous-surfaced, crusted nodular appearance. There was no evidence of metastasis.


Subject(s)
Humans , Eccrine Porocarcinoma , Lower Extremity , Neoplasm Metastasis , Poroma , Skin Neoplasms , Sweat Glands , Thumb
8.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-86893

ABSTRACT

Ansan, KoreaClear cell syringoma is a rare variant type of syringoma. It has two noteworthy features: histologic preponderance of clear cells and frequent coexistence with diabetes mellitus. There is no difference between clear cell syringoma and typical syringoma with respect to age, sex, and clinical features. We report a 48-year-old woman who presented with clear cell syringoma concomitant with diabetes mellitus. Histopathologic findings showed numerous various-sized, well-defined tumor cell nests composed largely of clear cells.


Subject(s)
Female , Humans , Middle Aged , Diabetes Mellitus , Syringoma
9.
Korean Journal of Dermatology ; : 1681-1682, 2000.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-217066

ABSTRACT

Mondor's disease is a uncommon disorder characterized by superficial thrombophlbitis, classically of thoracoabdominal wall. In about 50%-60% of cases, the cause is not determined, whereas in the others it is due to primary or secondary hypercoagulation requiring careful investigation. A 30-year- old woman presented a cord-like tender subcutaneous lesion on the left thoracoabdominal wall and histologic finding reveals thrombophlebitis. We found no evidence for primary and secondary hypercoagulable states.


Subject(s)
Female , Humans , Thrombophlebitis
10.
Annals of Dermatology ; : 299-302, 2000.
Article in English | WPRIM (Western Pacific) | ID: wpr-73457

ABSTRACT

The multifactorial etiology of BCC(basal cell carcinoma) are incompletely understood, including factors leading to multiple lesions in some patients. Cases of multiple BCCs reported in the literature have been associated with UV irradiation, inorganic arsenic poisoning, X-ray therapy, hematologic malignancy and several genodermatoses such as nevoid BCC syndrome, albinism, xeroderma pigmentosum. Multiple BCCs presented on the sun-protected areas, lacking predisposing risk factors which have been known, is rare skin condition. However, it suggests that there may be an unknown genetic susceptibility to the development of multiple BCCs. We report a rare case of multiple BCCs, which had developed only on the sun-protected areas in 64-year-old man, without any known predisposing causes.


Subject(s)
Humans , Middle Aged , Albinism , Arsenic Poisoning , Carcinoma, Basal Cell , Genetic Predisposition to Disease , Hematologic Neoplasms , Risk Factors , Skin , X-Ray Therapy , Xeroderma Pigmentosum
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