1.
Chem Commun (Camb)
; 54(100): 14148-14151, 2018 Dec 13.
Article
in English
| MEDLINE
| ID: mdl-30506077
ABSTRACT
A radical cascade cyclization of 2-alkynylthioanisoles with α-oxocarboxylic acids with AgNO3 has been described. This reaction provides a novel route to directly access 3-acylbenzothiophenes from simple chemical feedstocks. In particular, the utility of the approach was demonstrated by its application to the synthesis of a polymerization inhibitor and a raloxifene precursor.