ABSTRACT
Objective:To evaluate the reliability and validity of the Chinese version of behavioral activation for depression scale (C-BADS) in patients in methadone maintenance treatment (MMT).Methods:A total of 162 opioid addicts were recruited from the MMT programs in Wuhan city for the C-BADS investigation.Items analysis and exploratory factors analysis (EFA) were conducted with SPSS 21.0 and confirmatory factors analysis (CFA) was conducted with AMOS 24.0.Results:The correlation coefficients between subscales and total score were 0.228-0.813 (all P<0.01). Except for activation subscale, the correlation coefficients among subscales were lower than those between subscale dimensions and total score.The item-total score correlations coefficient were 0.060-0.716.Four factors were extracted by EFA, named avoidance/rumination(AR), activation(AC), social impairment(SI) and work/school impairment(WS) respectively, which the cumulative variance was 51.153%, and the factor loading of each item ranged from 0.328 to 0.797.The fitting indexes of CFA model were as following: χ 2/ df=1.594, CFI=0.839, TLI=0.820, IFI=0.844, RMSEA=0.069, SRMR=0.089.The Cronbach's α of the scale was 0.790, and the split-half reliability coefficient was 0.827. Conclusion:C-BADS has good internal consistency reliability and construct validity, but it still needs to be modified for the measurement of behavior activation of patients in MMT.
ABSTRACT
Objective:To evaluate the reliability and validity of the Reward Probability Index-Chinese version (C-RPI) among individuals with opioid dependence.Methods:A total of 160 individuals with opioid dependence were recruited from the methadone maintenance treatment(MMT) programs in Wuhan.The C-RPI was used in the investigation, and items/exploratory factors and confirmatory factors were adopted to analyze with IBM SPSS 22.0 and AMOS 24.0, respectively.Results:The correlation between each item and the total score of the scale was 0.325-0.657 (all P<0.01) and the item discrimination of the scale was good.Exploratory factor analysis extracted two factors, including reward probability and environmental suppressors, and a load of each item on its factor ranged from 0.519 to 0.744.The fitting indexes of confirmatory factor analysis were as follows: χ 2/ df=1.623, RMR=0.030, RMSEA=0.063, IFI=0.902, TLI=0.885, CFI =0.900.The internal consistency coefficient (Cronbach's α) of the C-RPI was 0.800; and there was no ceiling/floor effect on each dimension and total scale. Conclusion:The classification of dimensions for the C-RPI is reasonable, and the scale has good reliability and validity to measure the ability to obtain environmental rewards for individuals with opioid dependence.
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Objective To establish the HPLC Fingerprint of Pollen Typhae and give a new method for quality control of Pollen Typhae. Methods RP-HPLC was used on a YWG-C_ 18 column (250 mm?4.6 mm, 5 ?m) with the gradient elution solvent system composed of acetonitrile-0.05% H_3PO_4 water solution, the detection wavelength was 254 nm, sample injection was 5 ?L. Results HPLC Fingerprint of Pollen Typhae was established. Taking typhaneoside as the reference peak, 12 common peaks were selected as the fingerprint peaks of Pollen Typhae, the similarity between the fingerprint of eight batches of Pollen Typhae samples and reference fingerprint was determined. Conclusion The established HPLC fingerprint has desirable precision, reproducibility, and stability, and can be applied to the quality control of Pollen Typhae.
