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J Cutan Pathol ; 42(4): 285-8, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25384450

ABSTRACT

Neurofibromatosis type 1 is a relatively common genetic disorder with variable phenotypes. Tumors with features of both glomus tumors and neurofibromas are exceedingly rare in literature. Herein, we report a not yet described neoplasm with features of both a glomangioma/glomus tumor and a neurofibroma arising in a patient with segmental neurofibromatosis. Our case report supports the theory of a common lineage/ancestor cell between neurofibromas and glomus tumors and adds it to the spectrum of neoplasms that may arise in the setting of Von Recklinghausen's disease.


Subject(s)
Glomus Tumor/pathology , Neoplasms, Nerve Tissue/pathology , Neoplasms, Vascular Tissue/pathology , Neurofibroma/pathology , Neurofibromatosis 1/pathology , Diagnosis, Differential , Humans , Male , Middle Aged , Neoplasms, Nerve Tissue/diagnosis , Neoplasms, Nerve Tissue/genetics , Neural Crest/pathology , Neurofibroma/diagnosis , Neurofibroma/genetics , Neurofibromatosis 1/diagnosis , Neurofibromatosis 1/genetics , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology
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