ABSTRACT
Pearly penile papules (PPPs) are benign, dome-shaped lesions found around the corona of the penis. Despite being asymptomatic and benign in nature, the appearance of PPPs may cause a great deal of psychological distress to both the patient and their sexual partner. While patient reassurance may be the first-line treatment, several other treatment modalities including cryotherapy, electrodessication and curettage, and laser therapy have all been used to treat PPPs in order to achieve a cosmetic outcome that satisfies the patient. Based on the evaluation of the existing literature, ablative laser therapies offer satisfactory cosmetic outcomes with good long-term results.
Subject(s)
Cryotherapy/methods , Disease Management , Laser Therapy/methods , Penile Diseases/therapy , Penis/pathology , Humans , Male , Penile Diseases/pathologySubject(s)
Electrocoagulation/methods , Granulomatosis, Orofacial/surgery , Lymphangiectasis/surgery , Mouth Mucosa/pathology , Adolescent , Granulomatosis, Orofacial/complications , Granulomatosis, Orofacial/pathology , Humans , Lip , Lymphangiectasis/etiology , Lymphangiectasis/pathology , Male , Treatment OutcomeABSTRACT
Pembrolizumab is an immune checkpoint inhibitor with antitumor activity in other organ malignancies. We present this case -demonstrating multiple inflammatory adverse events associated with Pembrolizumab (in a single patient), in order to increase awareness and facilitate earlier identification of the wide-ranging cutaneous side effects associated with immunotherapy.
