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1.
Med J Malaysia ; 60(5): 614-23, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16515113

ABSTRACT

One hundred patients (101 eyes) with culture-proven bacterial keratitis were treated in the Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru, over a 4-year period. The majority of patients was male (63%), Malay (60%), from the Johor Bahru district (62%) and aged between 41 to 50 years (20%). The ocular predisposing factors were ocular trauma (41 eyes), ocular surface disease (28 eyes) and contact lens wear (26 eyes). The corneal ulcers were mainly large (50.5%), central (59.4%) and colonized by Gram-negative bacteria (78.1%). The most frequently isolated microorganisms were Pseudomonas aeruginosa (67 eyes), Staphylococcus aureus (12 eyes), Acinetobacter baumanii (6 eyes), Klebsiella pneumoniae (5 eyes), Corynebacterium sp. (3 eyes:) and Streptococcus pneumonliae (3 eyes). Twelve eyes (11.8%) had polymicrobial infection. A good visual outcome occurred in 52.5% of eyes analysed. Prognostic factors for visual outcome include presenting Snellen visual acuity, time to presentation after onset of ocular symptoms, ocular predisposing factor, corneal ulcer location and corneal ulcer size.


Subject(s)
Gram-Negative Bacteria/isolation & purification , Gram-Positive Bacteria/isolation & purification , Keratitis/epidemiology , Keratitis/microbiology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Hospitals, General , Humans , Infant , Infant, Newborn , Malaysia , Male , Middle Aged , Retrospective Studies
2.
Med J Malaysia ; 58(4): 565-78, 2003 Oct.
Article in English | MEDLINE | ID: mdl-15190633

ABSTRACT

A retrospective study was conducted at the Hospital Sultanah Aminah Johor Bahru to determine the outcome of trabeculectomy surgeries over a period of 4 years. One hundred and two eyes were followed up to a maximum of 63 months (mean 34.2 months). The 2-year survival rates for plain trabeculectomies, 5-Fluorouracil augmented trabeculectomies and Mitomycin-C augmented trabeculectomies were 52.9%, 27.3% and 60.5% respectively. The commonest complications noted were cataract formation (25%) and hyphaema (11%). Mitomycin-C induced complications were rarely seen. At last follow-up, 54% of eyes had intraocular pressures below 21 mmHg without medication, while 34% of eyes had intraocular pressures below 21 mmHg with medication. Vitreous at the trabeculectomy site was a statistically significant predictor of operative failure.


Subject(s)
Glaucoma/surgery , Trabeculectomy/methods , Adult , Aged , Aged, 80 and over , Antimetabolites/administration & dosage , Chemotherapy, Adjuvant , Combined Modality Therapy , Female , Fluorouracil/administration & dosage , Glaucoma/drug therapy , Hospitals, General , Humans , Malaysia , Male , Middle Aged , Mitomycin/administration & dosage , Nucleic Acid Synthesis Inhibitors/administration & dosage , Postoperative Complications , Retrospective Studies , Statistics, Nonparametric , Treatment Outcome
3.
Med J Malaysia ; 58(4): 579-86, 2003 Oct.
Article in English | MEDLINE | ID: mdl-15190634

ABSTRACT

Between 1st January 1999 and 31st December 2000, 452 foreign nationals were treated at the Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru. Eighty-five percent were male. The peak age range was from 21 to 30 years old. The patients were predominantly Indonesians (61%). A history of trauma was present in 63% of patients. Eight percent of eyes had severe visual impairment. Six patients (1.3%) were blind by WHO standards. Traumatic eye conditions, inflammatory/allergic eye conditions and degenerative eye conditions comprised 66%, 13% and 10% respectively of ocular pathology seen. The commonest ocular findings were corneal foreign body, corneal abrasion and subconjunctival haemorrhage.


Subject(s)
Eye Injuries/therapy , Hospital Departments/statistics & numerical data , Ophthalmology , Adolescent , Adult , Aged , Aged, 80 and over , Chi-Square Distribution , Child , Child, Preschool , Eye Injuries/epidemiology , Female , Humans , Infant , Infant, Newborn , Malaysia , Male , Middle Aged , Retrospective Studies , Transients and Migrants , Utilization Review
4.
Med J Malaysia ; 58(3): 405-12, 2003 Aug.
Article in English | MEDLINE | ID: mdl-14750381

ABSTRACT

Between 1st January 1999 and 31st December 2000, 152 patients (156 eyes) with open-globe injuries were treated in the Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru. The majority were male (88.2%), Malay (63.2%), from the Johor Bahru district (51.3%) and aged between 21 and 30 years (23.7%). Most injuries were workplace-related (41.4%). Lens injury, retinal detachment, endophthalmitis, intraocular foreign bodies and phthisis occurred in 40.4%, 15.4%, 14.7%, 12.2% and 11.5% of eyes respectively. A favourable visual outcome occurred in 55.4% of eyes. Prognostic factors for visual outcome include presenting visual acuity, relative afferent pupillary defect, wound location, lens injury, retinal detachment and endophthalmitis.


Subject(s)
Eye Injuries, Penetrating/epidemiology , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Hospitals, General , Humans , Infant , Malaysia/epidemiology , Male , Middle Aged
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