1.
Ann Intern Med
; 172(12): 841-842, 2020 06 16.
Article
in English
| MEDLINE
| ID: mdl-32539508
Subject(s)
Electronic Nicotine Delivery Systems , Lung Injury , Vaping , Humans , Lung Injury/etiology , Vaping/adverse effects
2.
Ann Intern Med
; 172(1): 57-58, 2020 01 07.
Article
in English
| MEDLINE
| ID: mdl-31590182
3.
Med Mycol
; 57(1): 122-126, 2019 Jan 01.
Article
in English
| MEDLINE
| ID: mdl-29618039
ABSTRACT
Candida species, traditionally viewed as opportunistic agents, are increasingly seen as a cause of infection in hospitalized patients. Treatment options are limited to a few classes of drugs. Increased resistance, especially by Candida glabrata, is problematic. We investigated the interaction between fluconazole and doxycycline or tigecycline, using clinically unique blood culture C. glabrata isolates. Eighteen isolates were screened using an Etest® MIC:MIC synergy method. With the doxycycline plus fluconazole combination, 28% of isolates showed synergy; tigecycline plus fluconazole showed 94% synergy. No antagonism was seen. The mechanisms of these interactions are unclear. Further research is warranted to assess clinical utility.