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[Immunomodulation characteristics of Lactobacillus genus bacteria].

Starovoitova, S O; Tymoshok, N O; Horchakov, V Iu; Spivak, M Ia.

Mikrobiol Z ; 71(3): 41-7, 2009.

Article in Ukrainian | MEDLINE | ID: mdl-19938605

ABSTRACT

Immunomodulation properties of the composition which contains live cells of bacteria of genus Lactobacillus: L. delbrueckii subsp. bulgaricus LB86 VKPM B-5788, L. delbrueckii subsp. delbrueckii DSM20074, L. rhmanosus LB3 IMB B-7038, L. acidophilus, L. rhamnosus VR were studied. Stimulation of phagocytic system under the influence of lactobacteria composition correlated with an increase of cytotoxic activity of natural killer cells and with their influence on synthesis of cytokines: interferon and tumor necrosis factor was shown.

Subject(s)

Immunity, Innate/drug effects , Immunologic Factors/pharmacology , Lactobacillus/physiology , Probiotics/pharmacology , Animals , Cell Line , Fibroblasts/drug effects , Fibroblasts/immunology , Interferon-alpha/blood , Killer Cells, Natural/immunology , Macrophages, Peritoneal/drug effects , Macrophages, Peritoneal/immunology , Mice , Phagocytosis/drug effects , Phagocytosis/immunology , Spleen/cytology , Spleen/drug effects , Spleen/immunology , Tumor Necrosis Factor-alpha/blood

ABSTRACT

Subject(s)

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