1.
Bioorg Med Chem Lett
; 8(3): 209-14, 1998 Feb 03.
Article
in English
| MEDLINE
| ID: mdl-9871656
ABSTRACT
Potent inhibitors of the 20S proteasome that contain a novel indanone head group coupled to di and tripeptides are described. These compounds are the first proteasome inhibitors have demonstrated high selectivity for the chymotrypsin-like activity of the 20S proteasome.