ABSTRACT
Fresh samples of heparinized human blood from 10 healthy nonsmoking volunteers were used to study the effect of the inhaled anesthetic sevoflurane on the oxygen half-saturation pressure of hemoglobin (P50) and on polarographic measurements of oxygen tension at low values. Control samples had a baseline P50 of 26.9 +/- 0.2 mm Hg. When the blood samples were exposed to 1.75% (1 minimum alveolar concentration, MAC), 2.75%, and 3.5% (2 MAC) of sevoflurane, the P50 values were 27.0 +/- 0.5 mm Hg, 27.1 +/- 0.4 mm Hg, and 26.9 +/- 0.5 mm Hg, respectively. Our present data show that 1 to 2 MAC sevoflurane has no significant effect on P50 (P greater than 0.05). Our data also show that sevoflurane did not interfere with polarographic measurements of oxygen tension (P greater than 0.05). Other inhaled agents--halothane, enflurane, and isoflurane--do interfere with these measurements, and we cannot explain the difference.
Subject(s)
Anesthesia, Inhalation , Ethers/pharmacology , Hemoglobins/analysis , Methyl Ethers , Oxygen/blood , Carbon Dioxide/blood , Dose-Response Relationship, Drug , Ethers/administration & dosage , Humans , In Vitro Techniques , SevofluraneABSTRACT
Testicular scan is an important method to improve the preoperative diagnosis of torsion of the testis. We used this method to diagnose torsion of the testis and for 3-month followup studies we correlated the followup scanning with testicular biopsy. We believe that one should always attempt to leave the twisted testicular portion in the scrotum because some vital cells might still be functioning.