The effects of type of recovery in resistance exercise on responses of platelet indices and hemodynamic variables.

To examine the effects of two different volume-matched resistance exercise (RE) recovery protocols (passive and active) on platelet indices and hemodynamic variables. Twelve Healthy participants (mean ± SD; 25 ± 3 yrs) completed a traditional resistance exercise (TRE) protocol that included three sets of six repetitions at 80% one repetition maximum (1RM) with two minutes passive recovery between sets, exercises and an interval resistance exercise (IRE) protocol that included three sets of six repetitions at 60%1RM followed by active recovery including six repetitions of the same exercise at 20%1RM. Blood samples for multiple platelet indices were taken before the protocols, immediately-post (IP), and after 1-hour recovery. Hemodynamic variables were measured before, IP, and every five minutes during recovery. Mean platelet volume and platelet large cell ratio P_LCR decreased from baseline to recovery. Heart rate (HR) and rate pressure product (RPP) were augmented at IP following IRE compared to TRE. HR was significantly elevated for 20 minutes after both RE protocols, and RPP recovered by five minutes. Systolic blood pressure was increased at IP compared to baseline and all recovery time points for both RE protocols. Our research demonstrated that both RE protocols, produced transient increases in platelet indices (MPV, and P_LCR) and hemodynamic variables (SBP, HR, and RPP), all of which returned to baseline within an hour. Notably, the IRE protocol elicited a greater increase in HR and RPP compared to the TRE protocol.

Effect of Resilience-based Group Therapy Intervention on Coping in Mothers of Children with Cancer: A Randomized Clinical Trial.

BACKGROUND: Cancer is the second most common cause of mortality after cardiovascular diseases (CVDs). Resilience is one of the best strategies for coping with diseases in patients with cancer. This study was aimed to determine the effect of resilience-based group therapy intervention on coping in mothers of children with cancer. MATERIALS AND METHODS: This randomized clinical trial was carried out on 48 mothers of children with cancer in Shahid Motahhari Hospital of Urmia, Iran, in 2017. Samples were randomly divided into two groups in Excel. The data were collected using a demographic questionnaire, the General Health Questionnaire (GHQ-28), and the Coping Health Inventory for Parents (CHIP). Analysis of variance (ANOVA) was used to compare the two groups at three different times. All p values of less than 0.05 were considered significant. RESULTS: A significant difference was observed in the mean scores of integration between the intervention group and control group (F1, 47 = 426.41, p < 0.001); the mean (standard deviation) of the integration score in the intervention and control groups was 40.80 (2.54) and 18.04 (3.05), respectively. Moreover, there was significant difference between the two groups in terms of the mean scores of social support and health status perception (F1, 47 = 176.59, p < 0.001). The mean (standard deviation) of social support and health status perception scores in the intervention group was 39.88 (2.81) and 22.72 (5.91) and in the control group was 16.87 (4.19) and 10.95 (2.01), respectively. CONCLUSIONS: Resilience-based group therapy intervention can be an effective strategy for coping with childhood cancer among mothers of children with cancer.

Characteristics of women applying for a legal abortion in the Islamic Republic of Iran.

BACKGROUND: Legal abortion has been permitted in the Islamic Republic of Iran since 2003 if there is serious and incurable disease that would cause the mother or the fetus suffering. AIMS: This study evaluated the characteristics of women applying for a legal abortion licence to the Tehran Province General Office of Legal Medicine, and compared the findings with earlier studies to evaluate changes over time. METHODS: All women visiting the office between August 2011 and 2012 to apply for a legal abortion licence were interviewed and sociodemographic data, reason for the application and outcome of the application were recorded. RESULTS: A total of 1378 women applied for a licence, and 48% were issued. Most applications (80.6%) were for fetal rather than maternal indications and 90.2% of the licences issued were for fetal indications. Most of the applications for fetal indications (53.7%) were granted a licence, while 75.7% for maternal indications were rejected. Neurological abnormalities in the fetus were the most common reason for the application (24.6%) and licences issued (30.7%). Neurological and psychological disorders were the most common maternal reason in all applications (25.7%) and in unsuccessful applications (28.6%). Cardiac disease (23.1%) was the most common maternal reason in successful applications. CONCLUSIONS: Comparison of the results with those of earlier studies shows an increase in the number of women applying for a legal abortion licence and in the number of licences issued. Similar studies are recommended to provide information on the effect of national abortion laws and help improve the legal abortion process in the Islamic Republic of Iran.

catena-Poly[[(2-amino-pyrimidine-κN(1))(thio-cyanato-κS)mercury(II)]-µ-thio-cyanato-κ(2)S:N].

In the title coordination polymer, [Hg(NCS)(2)(C(4)H(5)N(3))], the Hg(II) atom is four-coordinated by one aromatic N atom from a 2-amino-pyrimidine ligand, one S atom from a terminal thio-cyanate ligand, and one S atom and one N atom from a bridging thio-cyanate ligand. The crystal structure features polymeric chains running along the b axis which are stabilized by N-H⋯N hydrogen bonds.

The effect of human chorionic gonadotropin treatment on recipient mouse germ cell proliferation following spermatogonial stem cell transplantation of neonatal donor mice.

Spermatogonia are the male germ line stem cells whose life long expansion is needed for permanent production of spermatozoa. The present study was designed to examine the effect of hCG treatment on germ cell proliferation following stem cell transplantation in mice. Spermatogonial stem cells were isolated from neonatal mice testes and characterized by alkaline phosphatase, immunoreactivity and morphological analysis. hCG was injected into normal and cell transplanted mice. We then evaluated the testosterone levels and cell number in normal mice. After that, cyclin B1 gene expression was investigated in transplanted mice. Different doses of busulfan were injected to investigate the effects of chemotherapy on morphological criteria and preparation of recipient mice for transplantation. In this report we show proliferative potential of spermatogonial stem cells after cytotoxic treatment, transplantation efficiency by semi-quantitative RT-PCR, and hCG effect on stem cell regeneration in normal mice and following cell transplantation. The results indicate that spermatogonial stem cells can proliferate after transplantation, and the efficiency of their transplantation depends on hormonal treatment. Therefore, hormonal treatment after stem cell transplantation will be a powerful avenue for increasing the efficiency of transplantation and fertility restoration.