1.
J Org Chem
; 78(17): 8802-8, 2013 Sep 06.
Article
in English
| MEDLINE
| ID: mdl-23895217
ABSTRACT
We report an improved method for the selective deprotection of the N-phenylcarbamoyl group, which yields the corresponding alcohol without affecting other protecting groups. Deprotection was performed using di-tert-butyl dicarbonate and tetra-n-butylammonium nitrite (Boc2O and Bu4NNO2) in pyridine at room temperature. This method is also effective for deprotecting the fluorous N-phenylcarbamoyl group.