Plant growth regulators affecting canola (Brasica Napus L.) biochemistry including oil yield under drought stress.

The objective was to test the effects of PGR on canola (Brassica napus L.) biochemistry including oil yield under drought stress. A two-year (Y1 and Y2) split plot field experiment on the basis of a randomized complete block design with three replications was conducted. The main factor was, drought stress levels, including irrigation after a reduction of 40 (D1), 60 (D2) and 80% (D3) of field capacity (FC) moisture, and the sub-factor was PGR including control (S1), soil application of humic acid (S2), foliar applications of amino acid (S3), fulvic acid (S4) or seaweed extract (S5), and the combination of all PGR (S6). Although drought stress significantly decreased plant chlorophyll contents (a, b and total), oil percentage and oil yield, PGR significantly increased them. The D3 treatment, compared with control, decreased crop oil yield by 48.67 and 35.29% in the first and second year, respectively. However, treatment Y2D3S6 significantly increased oil percentage (43.10%) compared with control (40.97%). The PGR increased seed oil yield, in D3, by a maximum of 254 kg ha-1. The PGR numerically (p ≤ 0.0886) increased proline to 6.14 mg  g-1 LFW (Y1D3S6) compared with control (4.79 mg g-1 LFW). The PGR also significantly increased sugar content to 17.05 mg g-1 LFW, significantly different from the control (12.95 mg g-1 LFW). In conclusion, the tested PGR can improve the biochemical properties (quality) including oil yield of canola in drought stress conditions, which is of economic and health significance.

The effect of fetal liver-derived cell suspension allotransplantation on patients with diabetes: first year of follow-up.

Stem cell-based therapies have recently opened up new horizons for treatment of various types of diseases including diabetes mellitus. However, long-term efficacy and safety of these novel modalities still remain a serious question. Hereby, we aim to report the one-year follow-up results in the diabetic patients who underwent fetal liver-derived hematopoietic stem cell allotransplantation. Fifty six patients with type one (n=30) and type two (n=26) diabetes, aged 10-58 years old (32.8 ± 16.3) were divided into the intervention and placebo group. The patients in the intervention group underwent fetal liver-derived hematopoietic stem cell transplantation while the patients in the placebo group received 5 ml of normal saline both via an intravenous route. The patients were visited at regular intervals to evaluate the efficacy of transplantation in glycemic control as well as possible complications. In the 6th month of the follow-up, there was a significant decrease in HbA1c levels in all groups without any rise in the fasting c-peptide. However, none of the precipitants transiently or continuously became insulin free in the first year after transplantation. It can be concluded that, in this study, fetal liver-derived hematopoietic stem cell transplantation had no significant effects on glycemic control. The heterogeneity of our patients might account for the negative results. Hence, longer follow-up results will be reported in the near future.

Butachlor-induced acute toxic hepatitis.

Butachlor is a highly effective herbicidal substance widely used by farmers. We report a 60-year-old man with exfoliative dermatitis, jaundice, increase in liver enzymes and eosinophilia one day after accidental dermal exposure to butachlor toxin. The diagnostic workup showed no other cause and liver histology was consistent with substance-induced toxic hepatitis. Within two weeks of conservative therapy, his liver function tests returned to normal.