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1.
Int J Med Inform ; 159: 104669, 2022 03.
Article in English | MEDLINE | ID: mdl-34979435

ABSTRACT

Colorectal cancer is one of the leading causes of cancer-related death, worldwide. Early detection of suspicious tissues can significantly improve the survival rate. In this study, the performance of a wide variety of deep learning-based architectures is evaluated for automatic tumor segmentation of colorectal tissue samples. The proposed approach highlights the utility of incorporating convolutional neural network modules and transfer learning in the encoder part of a segmentation architecture for histopathology image analysis. A comparative and extensive experiment was conducted on a challenging histopathological segmentation task to demonstrate the effectiveness of incorporating deep modules in the segmentation encoder-decoder network as well as the contributions of its components. Experimental results demonstrate that shared DenseNet and LinkNet architecture is promising, achieves the state-of-the-art performance, and outperforms other methods with a dice similarity index of 82.74%±1.77, accuracy of 87.07%±1.56, and f1-score value of 82.79%±1.79.


Subject(s)
Colorectal Neoplasms , Neural Networks, Computer , Colorectal Neoplasms/diagnosis , Humans , Image Processing, Computer-Assisted/methods , Machine Learning
2.
Tissue Cell ; 58: 76-83, 2019 Jun.
Article in English | MEDLINE | ID: mdl-31133249

ABSTRACT

Melanoma is the most aggressive type of skin cancer, which significantly reduces the life expectancy. Early detection of melanoma can reduce the morbidity and mortality associated with skin cancer. Dermoscopic images acquired by dermoscopic instruments are used in computational analysis for skin cancer detection. However, some image quality limitations such as noises, shadows, artefacts exist that could compromise the robustness of the skin image analysis. Hence, developing an automatic intelligent system for skin cancer diagnosis with accurate detection rate is crucial. In this paper, we evaluate the performance of several state-of-the-art convolutional neural networks in dermoscopic images of skin lesions. Our experiment is conducted on a graphics processing unit (GPU) to speed up the training and deployment process. To enhance the quality of images, we employ different pre-processing steps. We also apply data augmentation methodology such as horizontal and vertical flipping techniques to address the class skewness problem. Both pre-processing and data augmentation could help to improve the final accuracy.


Subject(s)
Deep Learning , Dermoscopy , Image Processing, Computer-Assisted , Melanoma/diagnostic imaging , Skin Neoplasms/diagnostic imaging , Skin/diagnostic imaging , Humans
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