ABSTRACT
Two cases of malignant fibrous histiocytoma (MFH) of the breast are presented. The first case was a 63-year-old patient with MFH of myxoid type, the second case was a 79-year-old patient with MFH of pleiomorphic type. MFH is one of the most common tumors of the soft tissues, but its primary occurrence in the breast is rare. Immunohistochemical detection of antigens in the cytoplasm of histiocytes by antibdy LN 5 (Anti-Macrophage, BioGenex) can be helpful in rendering of the right diagnosis.
Subject(s)
Breast Neoplasms/pathology , Histiocytoma, Malignant Fibrous/pathology , Aged , Breast Neoplasms/diagnosis , Diagnosis, Differential , Female , Histiocytoma, Malignant Fibrous/diagnosis , Humans , Immunohistochemistry , Middle AgedABSTRACT
The authors present a rare case of the fish bone migration from the upper GIT into the liver parenchyma. Furthermore, a possibility of the diagnostics and management of its rare complication- an inflammatory pseudotumor of the liver is presented. Based on the literature data, other possible complications of foreign objects in the liver parenchyma are listed, including their diagnostic and treatment options.
Subject(s)
Granuloma, Foreign-Body/diagnosis , Liver Diseases/diagnosis , Aged , Bone and Bones , Foreign-Body Migration/complications , Gastrointestinal Tract , Granuloma, Foreign-Body/pathology , Granuloma, Foreign-Body/surgery , Humans , Liver Diseases/pathology , Liver Diseases/surgery , MaleABSTRACT
Oncocytic cardiomyopathy is a rare arrhythmogenic disorder usually associated with female sex, difficult-to-control arrhythmias, or sudden death of infants and children. Morphologically, it is characterized by the presence of oncocytic cells, which are diffusely distributed or form the nodular structures within the myocardium, occasionally involving the valves, with a large number of mitochondria in cytoplasms. We present two cases of oncocytic cardiomyopathy. The first case had a fatal clinical outcome, and the other case was surgically treated. The nuclear expression of skeletal muscle transcription factor MyoD1 was demonstrated in the first case, supporting the theory that oncocytic cardiomyopathy is a conduction system developmental disorder. To confirm this hypothesis, it is necessary to further investigate myogenic transcription factor program in human cardiac conduction system cells.
