Vitamin B1 in the treatment of leprosy. 1- Vitamin B1 excretion in urine

1- Among thirty-one patients selected from a leprosarium the urinary excretion of vitamin B1 was found to be either nil or far below normal. 2- Following the oral administration of moderately large doses of vitamin B1 the urinary excretion rapidly increased, the response being similar to that observed in normal individuals. 3- The urinary excretion of vitamin B1 among lepers after parenteral administration was similar to that following oral administration. 4- Vitamin B1 excretion during treatment with that substance was apparently not influenced by factors such as fever, parenteral administration of chaulmoogra preparations or iodides, the duration of the disease, or the type of the lesions.