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1.
Neuropediatrics ; 37(2): 110-3, 2006 Apr.
Article in English | MEDLINE | ID: mdl-16773512

ABSTRACT

Kearns-Sayre syndrome (KSS) is a mitochondrial disorder consisting of external ophthalmoplegia, retinitis pigmentosa, ataxia and heart block. Magnetic resonance imaging (MRI) shows abnormal T2 high signal intensity in the deep gray matter nuclei, the cerebellar and the subcortical white matter. We report an unusual MR pattern of KSS, where the T2 images revealed radially oriented, hypointense stripes in hyperintense white matter, a characteristic MRI pattern of lysosomal disease not previously reported in KSS.


Subject(s)
Brain/pathology , Kearns-Sayre Syndrome/pathology , Adult , Humans , Magnetic Resonance Imaging , Male
4.
Skeletal Radiol ; 32(10): 567-74, 2003 Oct.
Article in English | MEDLINE | ID: mdl-12942204

ABSTRACT

OBJECTIVE: To assess the role of a limited MR protocol (coronal STIR) as the initial part of the MR examination in patients with hip pain. DESIGN AND PATIENTS: Eighty-five patients presenting with hip pain, and normal radiographs of the pelvis, and who underwent our full MR protocol for hips were included retrospectively in the study. The full protocol consists of coronal T1-weighted and short tau inversion-recovery (STIR), and axial T2-weighted sequences. Ninety-three MR examinations were performed. Two radiologists interpreted the STIR (limited) examinations and the full studies separately, masked to each other's findings and to the final diagnosis. Comparison between the two protocols was then undertaken. RESULTS: For both readers, all normal MR examinations on the coronal STIR limited protocol were normal on the full protocol, with an interobserver reliability of 0.96. The STIR protocol was able to detect the presence or absence of an abnormality in 100% of cases (sensitivity). The STIR-only protocol provided a specific diagnosis in only 65% of cases (specificity). CONCLUSION: A normal coronal STIR study of the hips in patients with hip pain and normal radiographs precludes the need for further pelvic MR sequences. Any abnormality detected on this limited protocol should be further assessed by additional MR sequences.


Subject(s)
Arthralgia/diagnostic imaging , Arthralgia/pathology , Hip Joint/diagnostic imaging , Hip Joint/pathology , Magnetic Resonance Imaging/methods , Adolescent , Adult , Aged , Aged, 80 and over , Arthralgia/etiology , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Radiography , Reproducibility of Results , Retrospective Studies , Sensitivity and Specificity
5.
Eur Radiol ; 9(9): 1879-81, 1999.
Article in English | MEDLINE | ID: mdl-10602968

ABSTRACT

Malformations of the lower limbs are rare and heterogeneous anomalies. To explain the diversity and complexity of these abnormalities, authors introduced the concept of tibial and fibular developmental fields. Defects in these fields are responsible for different malformations, which have been described, to our knowledge, in only one report in the radiology literature. We present a case of a newborn with femoral bifurcation, absent fibulae and talar bones, ankle and foot malformations, and associated atrial septal defect. Our case is an example of defects in both fibular and tibial developmental fields.


Subject(s)
Abnormalities, Multiple , Fibula/abnormalities , Limb Deformities, Congenital/diagnostic imaging , Tibia/abnormalities , Abnormalities, Multiple/diagnosis , Fibula/diagnostic imaging , Humans , Infant, Newborn , Male , Radiography , Tibia/diagnostic imaging
6.
Am Surg ; 49(4): 209-10, 1983 Apr.
Article in English | MEDLINE | ID: mdl-6881729

ABSTRACT

Nuclear scanning appears to be a useful test to screen patients with penetrating injuries to the extremities who have proximity as the only finding suggestive of vascular injury. Patients with abnormal scans should be further studied with standard angiography. Interpretation of the scan is dependent on the reader's experience.


Subject(s)
Arm Injuries/diagnostic imaging , Arteries/injuries , Leg Injuries/diagnostic imaging , Angiography , Arteries/diagnostic imaging , Evaluation Studies as Topic , Humans , Radionuclide Imaging , Sulfur , Technetium , Technetium Tc 99m Sulfur Colloid
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