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Neural Comput ; 36(7): 1433-1448, 2024 Jun 07.
Article in English | MEDLINE | ID: mdl-38776953

ABSTRACT

Mean-field models are a class of models used in computational neuroscience to study the behavior of large populations of neurons. These models are based on the idea of representing the activity of a large number of neurons as the average behavior of mean-field variables. This abstraction allows the study of large-scale neural dynamics in a computationally efficient and mathematically tractable manner. One of these methods, based on a semianalytical approach, has previously been applied to different types of single-neuron models, but never to models based on a quadratic form. In this work, we adapted this method to quadratic integrate-and-fire neuron models with adaptation and conductance-based synaptic interactions. We validated the mean-field model by comparing it to the spiking network model. This mean-field model should be useful to model large-scale activity based on quadratic neurons interacting with conductance-based synapses.


Subject(s)
Action Potentials , Models, Neurological , Neural Networks, Computer , Neurons , Neurons/physiology , Action Potentials/physiology , Synapses/physiology , Humans , Animals , Computer Simulation , Nerve Net/physiology
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