ABSTRACT
Congenital hyperinsulinism (CHI) is a rare and heterogeneous disease with a challenging diagnostic process and a need of individualised treatment of each patient. In severe, neonatal or infant CHI, differentiation between the focal and diffuse form by rapid genetics, 18F-fluoro-L-dihydroxyphenylalanine positron emission tomography/computed tomography and peroperative microscopy of frozen section allows surgeons to resect the focal lesion instead of performing subtotal pancreatectomy. Milder CHI, sometimes difficult to diagnose, is treated conservatively. In spite of all improvements, cerebral complications are still frequently seen.
Subject(s)
Congenital Hyperinsulinism , Congenital Hyperinsulinism/diagnosis , Congenital Hyperinsulinism/etiology , Congenital Hyperinsulinism/genetics , Congenital Hyperinsulinism/pathology , Genetic Testing , Genotype , Humans , Infant , Infant, Newborn , Mutation , PhenotypeABSTRACT
A case of colocolonic invagination is presented. The mass was palpated preoperatively and diagnosed by barium enema X-ray and ultrasound. Operation confirmed the diagnosis and demonstrated a coecum tumor. The patient was treated successfully with a right hemicolectomy.
Subject(s)
Adenocarcinoma/diagnosis , Cecal Neoplasms/diagnosis , Intussusception/diagnosis , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/surgery , Cecal Neoplasms/diagnostic imaging , Cecal Neoplasms/surgery , Colectomy , Female , Humans , Intussusception/diagnostic imaging , Intussusception/etiology , Middle Aged , RadiographyABSTRACT
Children of all ages may develop gallstones. Ultrasonography is the diagnostic method of choice if gallstones are suspected. In children having gallstones diagnosed as a result of ultrasonography carried out due to different indication expectant treatment is recommended. Children presenting with typical clinical signs of gallstone colic need an operation. Laparoscopic cholecystectomy is the recommended choice, as data are lacking on the risk of recurrence of gallstones after cholecystolithotomy. Postoperative complications are few in otherwise healthy children.
