ABSTRACT
T-cell posttransplant lymphoproliferative disorders are rare, with peripheral T-cell lymphoma not otherwise specified being the most common type. Although cases of the signet ring cell variant of primary cutaneous CD30+ lymphoproliferative disorder have been reported, such cases have not been described in the posttransplant setting. We describe a case with emphasis on the special contextual differential diagnostic considerations.
Subject(s)
Biomarkers, Tumor/analysis , Heart Transplantation/adverse effects , Ki-1 Antigen/analysis , Lymphoma, T-Cell, Cutaneous/pathology , Lymphoproliferative Disorders/pathology , Skin Neoplasms/pathology , Biopsy , Humans , Immunohistochemistry , Immunosuppressive Agents/adverse effects , Lymphoma, T-Cell, Cutaneous/etiology , Lymphoma, T-Cell, Cutaneous/genetics , Lymphoma, T-Cell, Cutaneous/immunology , Lymphoproliferative Disorders/etiology , Lymphoproliferative Disorders/genetics , Lymphoproliferative Disorders/immunology , Male , Middle Aged , Predictive Value of Tests , Skin Neoplasms/etiology , Skin Neoplasms/genetics , Skin Neoplasms/immunologyABSTRACT
Staphylococcus aureus is a common pathogen in clinical infectious disease. The cutaneous manifestations can vary dramatically from a simple infected hair follicle to a life-threatening illness such as toxic shock syndrome or staphylococcal scalded skin syndrome. The authors review the variety of manifestations of various S aureus infections on the skin.
Subject(s)
Staphylococcal Skin Infections/diagnosis , Staphylococcal Skin Infections/physiopathology , Staphylococcus aureus , Education, Medical, Continuing , HumansABSTRACT
OBJECTIVE: Commercial fishing is one of the most dangerous professions with many of the occupational health problems related to the skin. This study elucidates the types of occupational skin disorders that occur in commercial fishermen in North Carolina. STUDY DESIGN/SETTINGS: Booths were set up offering free skin cancer screenings at various seafood festivals, a "blessing of the fleet" event and commercial fishing shows, which were located throughout eastern North Carolina from 2002-2004. When commercial fishermen were screened, they were asked about significant skin problems that they had experienced and were related to their occupation. They were specifically asked about their history of (1) cancerous and precancerous skin lesions, (2) eczemas, (3) superficial fungal infections, (4) bacterial infections of the skin, (5) traumatic injuries related to the skin, (6) bites and stings, (7) shocks from fish, and (8) skin problems related to environmental extremes. RESULTS: Eighty-one North Carolina watermen were screened: seven of the fishermen (9%) had at least one basal cell carcinoma, five (6%) had at least one squamous cell carcinoma, and no melanomas were detected. Many occupationally related skin disorders were noted on the historical survey, and some of the more dangerous of these included traumatic injuries related to fishing equipment, cutaneous cancers, fish bites, infections, stingray injuries, and man-of-war stings. LIMITATIONS: The sample population was comprised of volunteers, which limits generalizability, and some diagnoses were established retrospectively. CONCLUSIONS: There are a wide variety of skin disorders among commercial fishermen in North Carolina and healthcare professionals should be aware of these when working with watermen.
