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Chem Commun (Camb) ; 59(42): 6339-6342, 2023 May 23.
Article in English | MEDLINE | ID: mdl-37186113

ABSTRACT

3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 102 CFU cm-2 for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.


Subject(s)
Metal Nanoparticles , Photochemotherapy , Gold/chemistry , Metal Nanoparticles/chemistry , Polyphenols , Spectrum Analysis, Raman
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