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1.
Int J Biol Macromol ; 267(Pt 1): 131217, 2024 May.
Article in English | MEDLINE | ID: mdl-38552683

ABSTRACT

Ultrasonic assisted acetic acid hydrolysis was applied to prepare starch nanocrystals (SNCs) from native starches with different crystalline structures (A, B, and C types). The structure properties, morphology, Pickering emulsion stability and curcumin deliver capacity of both SNCs and native starches were investigated and compared. Compared with native starches, SNCs showed smaller size and higher crystallinity. The size of SNCs varied with different crystalline types, with C-type starch exhibiting the smallest SNCs (107.4 nm), followed by A-type (113.8 nm), and B-type displaying the largest particle size (149.0 nm). SNCs-Pickering emulsion showed enhanced stability with smaller emulsion droplets, higher static stability, and denser oil/water interface. SNCs-Pickering emulsions displayed higher curcumin loading efficiency (53.53 %-61.41 %) compared with native starch-Pickering emulsions (13.93 %-19.73 %). During in vitro digestion, SNCs-Pickering emulsions proved to be more proficient in protecting and prolonging the biological activity of curcumin due to their smaller size and better interfacial properties. These findings demonstrated the potential of SNCs for application in Pickering emulsion and delivery of bioactive components.


Subject(s)
Acetic Acid , Curcumin , Emulsions , Nanoparticles , Starch , Curcumin/chemistry , Starch/chemistry , Emulsions/chemistry , Nanoparticles/chemistry , Acetic Acid/chemistry , Particle Size , Drug Stability , Hydrolysis , Crystallization , Ultrasonic Waves , Drug Carriers/chemistry
3.
BMJ Open ; 14(2): e077078, 2024 Feb 10.
Article in English | MEDLINE | ID: mdl-38341212

ABSTRACT

OBJECTIVES: To investigate the prevalence of depression and anxiety symptoms among older adults in an urban district in China, as well as their associated factors. DESIGN: Cross-sectional study. SETTING: General communities in Shenzhen, Guangdong, China. PARTICIPANTS: A total of 5372 community-dwelling older adults aged 65 years or older were initially recruited. Ultimately, 5331 participants met the inclusion criteria and were included in this study. METHODS: Participants completed a sociodemographic questionnaire, along with assessments including the Patient Health Questionnaire-9, Generalised Anxiety Scale-7, UCLA Loneliness Simplification Scale, Insomnia Severity Index Scale (ISI), Community Dementia Brief Screening Scale and the 8-item Dementia Screening Questionnaire. Statistical analyses included the Shapiro-Wilk test, independent t-test, Wilcoxon rank test, χ2 test and univariate and multivariate linear regression analysis. RESULTS: The prevalence of depression and anxiety symptoms among older adults in Shenzhen communities was 10.4% and 11.3%, respectively. In multivariate analysis, age (B=-0.01, p<0.05), relatively poor health status in the past year (B=1.00, p<0.01), poor health status in the past year (B=2.40, p<0.01), ISI score (B=0.21, p<0.01), -item Ascertain Dementia Questionnaire (AD8) score (B=0.22, p<0.01), UCLA Loneliness Scale (ULS) score (B=0.24, p<0.01) were significantly associated with the severity of depression symptom, Compared with their respective reference categories, relatively poor health status in the past year (B=0.50, p<0.01), poor health status in the past year (B=1.32, p<0.01), ISI score (B=0.23, p<0.01), sleep duration (B=0.05, p<0.01), AD8 score (B=0.21, p<0.01), Community Screening Instrument for Dementia score (B=0.13, p<0.01), ULS score (B=0.22, p<0.01) were significantly associated with the severity of anxiety symptom. CONCLUSIONS: We observed a high prevalence of depression and anxiety symptoms among older adults in this study. The existing welfare system and infrastructure should remain and targeted mental health programmes addressing the identified risk factors should be proposed.


Subject(s)
Dementia , Depression , Humans , Aged , Cross-Sectional Studies , Prevalence , Depression/psychology , Anxiety/psychology , China/epidemiology , Dementia/epidemiology
4.
J Affect Disord ; 351: 661-670, 2024 Apr 15.
Article in English | MEDLINE | ID: mdl-38309483

ABSTRACT

BACKGROUND: Observational studies cannot accurately infer the causal associations between oral health status and psychiatric disorders. METHODS: We conducted univariate and multivariate Mendelian randomization (MR) analyses using single nucleotide polymorphisms (SNPs) associated with eight oral health statuses (periodontitis, DMFS, Nteeth, toothache, loose teeth, painful gums, bleeding gums, and mouth ulcers) and four psychiatric disorders (Schizophrenia, Major Depressive Disorder (MDD), anxiety and stress-related disorder (ASRD), and Bipolar Disorder (BIP)) as instrumental variables. Genetic data were sourced from the Gene-lifestyle interactions in dental endpoints (GLIDE), UK Biobank, Psychiatric Genomics Consortium (PGC), and Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH). The inverse variance-weighted (IVW) approach, supported by a comprehensive sensitivity analysis, was employed. RESULTS: Genetically predicted mouth ulcers were significantly linked to higher MDD (OR = 2.17, 95 % CI: 1.33--3.54, P< 0.01) and BIP risks (OR = 2.25, 95 % CI: 1.22-4.15, P = 0.01). BIP heightened bleeding gums risk (OR = 1.01, 95 % CI: 1.00-1.01, P < 0.01). These associations were adjusted for smoking status and alcohol consumption. Painful gums were significantly associated with MDD risk (OR = 96.48, 95 % CI: 2.66-3495.28, P = 0.01), while MDD raised periodontitis risk (OR = 2.15, 95 % CI: 1.24-3.75, P = 0.01), both confounded by smoking and alcohol. Relatively small effects between several variables, while others could not withstand correction for multiple tests. LIMITATIONS: The sample size and limitation to European populations limits the study generalizability. CONCLUSIONS: This study provide evidence of possible causal relationships between several oral health conditions and mental illness. Focusing on oral health and valuing mental health are important for each other and overall health.


Subject(s)
Depressive Disorder, Major , Mental Disorders , Oral Ulcer , Periodontitis , Humans , Oral Health , Depressive Disorder, Major/epidemiology , Depressive Disorder, Major/genetics , Mendelian Randomization Analysis , Mental Disorders/epidemiology , Mental Disorders/genetics , Genome-Wide Association Study , Polymorphism, Single Nucleotide
5.
Food Chem ; 439: 138134, 2024 May 01.
Article in English | MEDLINE | ID: mdl-38064837

ABSTRACT

Ethanol-acid penetration and drying-heating treatment was developed to shorten the preparation time and improve the quality of starch nanocrystals (SNCs). After treatment by optimized parameters, including 40 % ethanol solution, 10.6 mM chloric acid, and heating time of 1.5 h or 2.0 h, the starches exhibited weakened internal structure and relatively complete crystalline structure. Compared with the regular preparation of only acid hydrolysis, the regular final yield (8.5 % after 5 days) was reached in 48 h and 12 h of the starch heated at 1.5 h and 2.0 h, respectively. The micromorphology, molecular weight, and crystalline structure evaluation demonstrated that the collected nanoparticles were indeed SNCs with smaller size and higher relative crystallinity than regular SNCs. Further analysis found that the SNCs had better crystalline lamellae, higher thermal stability, and lower proportion of phosphorus and sulfur atoms than regular SNCs. This provided a potential method for the high-efficiency preparation of SNCs.


Subject(s)
Nanoparticles , Starch , Starch/chemistry , Ethanol , Heating , Particle Size , Acids , Nanoparticles/chemistry
6.
Spectrochim Acta A Mol Biomol Spectrosc ; 308: 123774, 2024 Mar 05.
Article in English | MEDLINE | ID: mdl-38141503

ABSTRACT

Carbonaceous fluid within mineral-hosted inclusions provides important information for carbon cycle in deep Earth. In addition to CH4 and CO2, heavy hydrocarbons (e.g., C2H6 and C3H8) are frequently observed in carbonaceous fluid inclusions (i.e, wet gas inclusions with C1/∑Ci < 0.95). However, determination of the composition of such complex volatiles is difficult based on traditional microthermometric measurements. Here we carried out experimental calibrations on Raman spectroscopic measurements of the pressure (P) and composition of the CH4 ± C2H6 ± C3H8 ± H2S system at room temperature and 0.1-130 MPa. We confirmed that the C-H symmetric stretching vibration band of CH4 [ν1(CH4), ∼2917 cm-1] shifted to lower wavenumber with rising pressure, thus the P-ν1(CH4) relationship could be applied to calculate the pressure of wet gas. It should be noted that the presence of C2+ and/or H2S will shift the [ν1(CH4)] to lower wavenumber at constant pressure (with the order of C3H8 ≥ H2S > C2H6). Obviously, the P-ν1(CH4) relationship derived from pure CH4 system could not be simply applied to wet gas inclusion, otherwise the pressure would be overestimated. To avoid the overlap of the C-H vibrations of CH4, C2H6 and C3H8, the peak areas and peak heights of the overtone vibration of CH4 [2ν4(CH4), ∼2580 cm-1], C-C symmetric stretching vibrations of C2H6 [ν3(C2H6), ∼995 cm-1] and C3H8 [ν8(C3H8), ∼868 cm-1], and S-H symmetric stretching vibration of H2S [ν1(H2S), ∼2612 cm-1] were fitted using Gaussian + Lorentz functions. The obtained peak areas and peak heights were then used to calculate the Raman quantification factors (F factor and G factor, respectively) of C2H6, C3H8 and H2S relative to CH4, respectively. Both the F factor and G factor increased with rising pressure, whereas the FC2H6, FC3H8 and GH2S kept nearly constant at ∼5.69, 6.39 and 153.8, respectively in high pressure gas mixtures (e.g., >30 MPa). Therefore, for inclusions with higher internal pressure, the molar ratio of CH4, C2H6, C3H8 and H2S could be determined by the aforementioned F and G factors. This method was applied to the calcite-hosted single-phase gas inclusions in the Upper Permian Changxing Formation carbonate reservoir from the eastern Sichuan Basin (South China). Our results indicated that the trapping pressure would be obviously overestimated if the presence of heavy hydrocarbons was not taken into account.

7.
Sci Rep ; 13(1): 21348, 2023 Dec 04.
Article in English | MEDLINE | ID: mdl-38049524

ABSTRACT

Rich in renewable resources, extensive acreage, and bioenergy expertise, Brazil, however, has no established strategies for sustainable aviation fuels, particularly e-kerosene. We extend the lens from the often-studied economic feasibility of individual e-kerosene supply chains to a system-wide perspective. Employing energy system analyses, we examine the integration of e-kerosene production into Brazil's national energy supplies. We introduce PyPSA-Brazil, an open-source energy system optimisation model grounded in public data. This model integrates e-kerosene production and offers granular spatial resolution, enabling federal-level informed decisions on infrastructure locations and enhancing transparency in Brazilian energy supply scenarios. Our findings indicate that incorporating e-kerosene production can bolster system efficiency as Brazil targets a carbon-neutral electricity supply by 2050. The share of e-kerosene in meeting kerosene demand fluctuates between 2.7 and 51.1%, with production costs varying from 113.3 to 227.3 €/MWh. These costs are influenced by factors such as biokerosene costs, carbon pricing, and export aspirations. Our findings are relevant for Brazilian policymakers championing aviation sustainability and offer a framework for other countries envisioning carbon-neutral e-kerosene production and export.

8.
Sci Rep ; 13(1): 17877, 2023 10 19.
Article in English | MEDLINE | ID: mdl-37857639

ABSTRACT

Studies considering the relationship between non-obesity-related body composition and lung function are few; therefore, this study aimed to explore these correlations and effects. This cross-sectional study conducted in rural Qingtongxia City and Pingluo County, Ningxia, China, included 776 participants aged 30-75 years. Body composition and lung function were measured using direct segmental multifrequency bioelectrical impedance analysis and a digital spirometer, respectively. Their correlation was assessed using partial correlation analysis, controlling for age and smoking status, and the body composition effect on lung function was analyzed using binomial logistic regression analysis. The body components total body water content, protein content, mineral content, muscle mass, fat-free mass (FFM), skeletal muscle mass, basal metabolic volume, and chest circumference (CC) positively correlated with pulmonary function (forced vital capacity and forced expiratory volume in one second) in both sexes. Neck circumference and hip circumference positively correlated with pulmonary function in women. Additionally, lung function declines more slowly in women (odds ratio [OR] = 0.66, 95% confidence interval [CI] = 0.44-0.98, p = 0.04); CC (OR = 0.92, 95% CI = 0.86-0.98, p = 0.01) increased as a protective factor for decreased lung function. Increased waist circumference (OR = 1.04, 95% CI = 1.00-1.09, p = 0.04) was a risk factor for reduced lung function. FFM contains body composition indicators positively correlating with lung function, excluding fat-related body composition. Abdominal obesity increases the risk of decreased lung function.


Subject(s)
Body Composition , Lung , Male , Humans , Female , Cross-Sectional Studies , Body Mass Index , Body Composition/physiology , Obesity/epidemiology
9.
Angew Chem Int Ed Engl ; 62(47): e202314213, 2023 Nov 20.
Article in English | MEDLINE | ID: mdl-37794843

ABSTRACT

Poly(heptazine imide) (PHI) salts, as crystalline carbon nitrides, exhibit high photocatalytic activity and are being extensively researched, but its photochemical instability has not drawn researchers' attention yet. Herein, sodium PHI (PHI-Na) ultrathin nanosheets with increased crystallinity, synthesized by enhancing contact of melamine with NaCl functioning as a structure-induction agent and hard template, exhibits improved photocatalytic hydrogen evolution activity, but low photochemical stability, owing to Na+ loss in the photocatalytic process, which, interestingly, can be enhanced by the common ion effect, e.g., addition of NaCl that is also able to remarkably increase the photoactivity with the apparent quantum yield at 420 nm reaching 41.5 %. This work aims at attracting research peers' attention to photochemical instability of PHI salts and provides a way to enhance their crystallinity.

10.
J Am Chem Soc ; 145(33): 18578-18590, 2023 08 23.
Article in English | MEDLINE | ID: mdl-37553999

ABSTRACT

Bimolecular or tetramolecular G-quadruplexes (GQs) are predominantly self-assembled by the same sequence-identical G-rich oligonucleotides and usually remain inert to the strand displacement reaction (SDR) with other short G-rich invading fragments of DNA or RNA. Appealingly, in this study, we demonstrate that a parallel homomeric bimolecular GQ target of Tub10 d(CAGGGAGGGT) as the starting reactant, although completely folded in K+ solution and sufficiently stable (melting temperature of 57.7 °C), can still spontaneously accept strand invasion by a pair of short G-rich invading probes of P1 d(TGGGA) near room temperature. The final SDR product is a novel parallel heteromeric trimolecular GQ (tri-GQ) of Tub10/2P1 reassembled between one Tub10 strand and two P1 strands. Here we present, to the best of our knowledge, the first NMR solution structure of such a discrete heteromeric tri-GQ and unveil a unique mode of two probes vs one target in mutual recognition among G-rich canonical DNA oligomers. As a model system, the short invading probe P1 can spontaneously trap G-rich target Tub10 from a Watson-Crick duplex completely hybridized between Tub10 and its fully complementary strand d(ACCCTCCCTG). The Tub10 sequence of d(CAGGGAGGGT) is a fragment from the G-rich promoter region of the human ß2-tubulin gene. Our findings provide new insights into the Hoogsteen pairing-based SDR between a GQ target and double invading probes of short G-rich DNA fragments and are expected to grant access to increasingly complex architectures in GQ-based DNA nanotechnology.


Subject(s)
G-Quadruplexes , Humans , DNA/chemistry , Oligonucleotides/chemistry , Recombination, Genetic , RNA
11.
Int J Biol Macromol ; 253(Pt 1): 126604, 2023 Dec 31.
Article in English | MEDLINE | ID: mdl-37652338

ABSTRACT

To prevent starch nanocrystals (SNCs) that are generated at an early stage from being hydrolyzed excessively, this study proposed a new separation method, named "neutral dispersion and acidic precipitation." SNCs were prepared from waxy potato starch by sulfuric acid hydrolysis. Based on the results of kinetics and molecular weight, the hydrolysis was divided into three stages, e.g., rapid (initial 1 day), medium (subsequent 1 day) and slow stage (2-5 days). The rapid and medium stages were related to the degradation of amorphous region in starch, and the slow stage mainly referred to SNC release. Therefore, the method was developed to separate SNCs at the slow stage. After centrifugation at 6000 rpm, large particles were removed from the SNC suspension under pH 7. The SNCs with small average size and crystallite size, high relative crystallinity (RC), and high dispersion stability in the supernatant were retained and were then precipitated entirely under pH 5, because pH 5 led to the reduction of dispersion stability of SNCs. Meanwhile, the hydrothermal and dry-thermal stability of separated SNCs were significantly promoted. The separation method has the potential in SNC preparation for increasing the yield and collecting products with small size and high RC.


Subject(s)
Nanoparticles , Starch , Starch/chemistry , Hydrolysis , Particle Size , Acids , Nanoparticles/chemistry , Amylopectin
12.
Food Chem ; 427: 136697, 2023 Nov 30.
Article in English | MEDLINE | ID: mdl-37379746

ABSTRACT

Quinoa starch nanoparticles (QSNPs) prepared by nanoprecipitation had a uniform particle size of 191.20 nm. QSNPs with amorphous crystalline structure had greater contact angle than QS with orthorhombic crystalline structure, which can therefore be utilized to stabilize Pickering emulsions. QSNPs-based Pickering emulsions prepared by suitable formulations (QSNPs concentration of 2.0-2.5 %, oil volume fraction of 0.33-0.67) exhibited good stability against pH of 3-9 and ionic strength of 0-200 mM. The oxidative stability of the emulsions increased with increasing starch concentration and ionic strength. Microstructural and rheological results indicated that the structure of the starch interfacial film and the thickening effect of the water phase affected the emulsion stability. The emulsion had excellent freeze-thaw stability and can be produced as a re-dispersible dry emulsion using the freeze-drying technique. These results implied that the QSNPs had great potential for application in the preparation of Pickering emulsions.


Subject(s)
Chenopodium quinoa , Nanoparticles , Emulsions/chemistry , Starch/chemistry , Chenopodium quinoa/chemistry , Nanoparticles/chemistry , Excipients , Water/chemistry , Particle Size
13.
ACS Appl Mater Interfaces ; 15(26): 31502-31513, 2023 Jul 05.
Article in English | MEDLINE | ID: mdl-37345282

ABSTRACT

The photoexcited charge separation efficiency of photocatalysts is generally considered as the key factor for enhancement of their photocatalytic activity, and sometimes, their photoabsorption capability and interfacial reaction kinetics play a key part, but the role of interfacial affinity of photocatalysts with substrates was rarely researched systematically. Herein, nitrogen vacancy-modified polymeric carbon nitride porous nanotubes (PCNpts) were simply synthesized, using tartaric acid as a crosslinking and corrosion agent, and exhibit a remarkable increment in surface area, wettability, photoabsorption and charge separation capability, and photocatalytic activity in water splitting to produce H2, but, interestingly, exhibit substrate-dependent variation of photoactivity in contaminant degradation, compared with bulk PCN. More interestingly, the interfacial affinity of PCNpts and PCN with contaminants and H2O, rather than photoabsorption and charge separation capability, is confirmed to dominate their photoactivity.

14.
Chemosphere ; 324: 138255, 2023 May.
Article in English | MEDLINE | ID: mdl-36854359

ABSTRACT

Airborne plastic particles have received increasing attention due to their ubiquity in the atmosphere and potential human health risks. Previous studies have demonstrated that early-life exposure to environmental toxicants is associated with abnormal metabolic function. However, the impact of exposure to polystyrene nanoplastics (PSNPs) through inhalation on the development of non-alcoholic fatty liver disease (NAFLD) in mothers and offspring remains unknown. In the present study, mice were gestationally exposed to PSNPs at different doses (0, 1, 5, and 25 µg µl-1) through inhalation to investigate health hazards to the dam at weaning and to adult offspring. Gestational exposure to PSNPs at high doses significantly induced hepatic steatosis in the dam and upregulated genes involved in de novo lipogenesis, fatty acids (FAs) uptake, and triacylglycerol (TG) synthesis in the monoacylglycerol acyltransferase pathway. Gestational exposure to high doses of PSNPs led to hepatic steatosis in adult female offspring but not male offspring, and expression levels of genes related to FAs uptake and TG synthesis in the glycerol 3-phosphate pathway were significantly elevated. Collectively, our data demonstrate that gestational exposure to airborne PSNPs induced different development processes of NAFLD in the dam and offspring, providing vital data about plastic particulate toxicology.


Subject(s)
Non-alcoholic Fatty Liver Disease , Humans , Mice , Animals , Female , Liver/metabolism , Polystyrenes/metabolism , Microplastics/metabolism , Lipogenesis
15.
Sci Data ; 10(1): 103, 2023 02 22.
Article in English | MEDLINE | ID: mdl-36813797

ABSTRACT

Improvements in modelling energy systems of populous emerging economies are highly decisive for a successful global energy transition. The models used-increasingly open source-still need more appropriate open data. As an illustrative example, we take the Brazilian energy system, which has great potential for renewable energy resources but still relies heavily on fossil fuels. We provide a comprehensive open dataset for scenario analyses, which can be directly used with the popular open energy system model PyPSA and other modelling frameworks. It includes three categories: (1) time series data of variable renewable potentials, electricity load profiles, inflows for the hydropower plants, and cross-border electricity exchanges; (2) geospatial data on the administrative division of the Brazilian federal states; (3) tabular data, which contains power plant data with installed and planned generation capacities, aggregated grid network topology, biomass thermal plant potential, as well as scenarios of energy demand. Our dataset could enable further global or country-specific energy system studies based on open data relevant to decarbonizing Brazil's energy system.

16.
Int J Biol Macromol ; 235: 123735, 2023 Apr 30.
Article in English | MEDLINE | ID: mdl-36806775

ABSTRACT

Starch nanoparticles (SNPs) were produced by nanoprecipitation combined with ultrasonication with the use of different starches (corn, potato and sago starch) and used to stabilize Pickering emulsions. The orthogonal experiment was used to optimize preparation conditions of gelatinization pretreatment duration of 30 min, ultrasonic power of 600 W, and ultrasonic time of 40 min. Compared with native starch, the SNPs were spherical in shape and displayed a V-type crystalline structure with low relative crystallinity and higher degree of double-helix. Compared with native starch-Pickering emulsion, the SNP-Pickering emulsion had a smaller droplet size, more uniform distribution, clearer oil/water interface, and higher static stability of droplets. The sago SNP-Pickering emulsion had the great gelatinous structure and emulsion stability. In addition, the SNP-Pickering emulsion had the better loading efficiency and controlled release performance of curcumin. Meanwhile, the bioavailability of curcumin in sago SNP-Pickering emulsion was highest.


Subject(s)
Curcumin , Nanoparticles , Emulsions/chemistry , Starch/chemistry , Nanoparticles/chemistry , Edible Grain , Particle Size
17.
ACS Nano ; 17(3): 2440-2449, 2023 02 14.
Article in English | MEDLINE | ID: mdl-36728677

ABSTRACT

Nanoplastics are common contaminants in the living environment. Thus far, no investigations have focused on small intestinal injury in the offspring of adult mice that were exposed to nanoplastics through the respiratory system during pregnancy. Here, we evaluated potential intestinal injury in the offspring of adult mice that were subjected to maternal 80 nm polystyrene nanoparticle (PS-NP) exposure during gestation. PS-NP exposure significantly reduced the birth weight of female mice compared with male mice. However, the adult body weights of the female and male offspring were substantially greater in the PS-NP-exposed groups. Additionally, we found that exposure to PS-NPs during pregnancy caused histological changes in the small intestines of both female and male offspring. Mechanistic analysis revealed upregulation of reactive oxygen species in the small intestines, as indicated by changes in the levels of superoxide dismutase (SOD) and malondialdehyde (MDA). Furthermore, exposure to PS-NPs led to downregulation of GPx4, FTH1, and FTL protein levels, indicating initiation of ferroptosis. Notably, the changes in mRNA expression levels of GPx4, FTH1, and FTL differed between female and male offspring. Although all phenotypes failed to demonstrate classic dose-dependent effects, the data imply that small intestinal toxicity is greater in female offspring than in male offspring. Our results suggest that PS-NP exposure during pregnancy causes sex-specific small intestinal toxicity, which might contribute to reactive oxygen species activation and subsequent ferroptosis. Overall, this study showed toxic effects in offspring after PS-NP exposure during pregnancy.


Subject(s)
Ferroptosis , Nanoparticles , Water Pollutants, Chemical , Pregnancy , Animals , Male , Female , Mice , Polystyrenes/toxicity , Microplastics/metabolism , Reactive Oxygen Species/metabolism , Down-Regulation , Nanoparticles/toxicity , Nanoparticles/metabolism
18.
Food Chem ; 412: 135536, 2023 Jun 30.
Article in English | MEDLINE | ID: mdl-36708668

ABSTRACT

Starch nanocrystals (SNCs) were prepared from waxy rice starch via sulfuric acid hydrolysis. The objective focused on the following: i) the hydrolysis kinetics and structural properties of SNCs; ii) the effects of differential centrifugation on the yield and size distribution of SNCs. The hydrolysis was divided into a rapid hydrolysis stage in the initial two days and a slow hydrolysis stage after two days. During the two-day hydrolysis, the average diameter of SNCs reached 244 nm. After two days of hydrolysis, the degree of crystallinity, crystallite size, and melting temperature and enthalpy increased. The proportion of A-branched chains decreased, whereas the proportion of B1-branched chains and molecular weight did not change considerably. Thus, the reaction in the slow hydrolysis stage could be considered as the surface modification and gradual release of SNCs. Furthermore, SNCs with a small size and high charge density could be used for differential centrifugation.


Subject(s)
Nanoparticles , Oryza , Starch/chemistry , Particle Size , Amylopectin , Hydrolysis , Nanoparticles/chemistry , Centrifugation
19.
Carbohydr Polym ; 298: 120137, 2022 Dec 15.
Article in English | MEDLINE | ID: mdl-36241303

ABSTRACT

Starch nanoparticles (SNPs) were prepared by rapid nanoprecipitation using coarse cereal starches, including quinoa, waxy proso millet, non-waxy proso millet, and maize starches (amylose content, 2.20 %-13.96 %). Morphology and dynamic light scattering analyses showed that the particle size of SNPs ranged from 190.35 nm to 310.25 nm. Ultrasonic pretreatment reduced the particle size. Quinoa and waxy proso millet SNPs swelled to flocculent, whereas non-waxy proso millet and maize SNPs showed spherical particles. Quinoa and waxy proso millet SNPs did not completely nucleate after nanoprecipitation. Quinoa SNPs formed a stable network in water, showing great viscoelastic behavior with higher G' and G''. Subsequently, the SNPs suspensions were used to prepare emulsions. The quinoa SNPs-based Pickering emulsion was the smallest and most uniform (12.96 µm), with great stability. These results suggested that the quinoa SNPs suspension with a stable network could be used as an efficient emulsifier for stabilizing Pickering emulsions.


Subject(s)
Chenopodium quinoa , Nanoparticles , Amylopectin , Amylose , Edible Grain , Emulsions , Particle Size , Rheology , Starch , Water
20.
Diabetes Metab Syndr Obes ; 15: 3243-3254, 2022.
Article in English | MEDLINE | ID: mdl-36304482

ABSTRACT

Background: In recent decades, obesity has become an epidemic worldwide and is a risk factor for many chronic diseases. Lung function is also a predictor of various chronic diseases. However, research results on the association between obesity and lung function are inconsistent and few studies have evaluated the association between central obesity indicators and lung function. Therefore, this study explored the correlation between central obesity and lung function. Methods: This study is a cross-sectional study. The basic participant characteristics were collected by questionnaire. A tape measure was used to measure waist circumference (WC) and hip circumference (HC). Body fat percentage was measured using an InBody370. Lung function parameters were measured using a digital spirometer connected to a computer (Chestgraph HI-101). R (R4.0.5) software was used for data analysis. A generalized linear model was used to analyze the association between obesity and lung function. Results: This study found that body mass index (BMI) adjusted for WC was negatively correlated with forced vital capacity (FVC) (ß=-0.05 [-0.06, -0.03] in men, ß=-0.05 [-0.07, -0.04] in women) and forced expiratory volume in 1 s (FEV1)(ß=-0.02 [-0.03, -0.00] in men, ß=-0.03 [-0.04, -0.02] in women). Body fat percentage was negatively correlated with FVC (ß=-0.01 [-0.01, -0.01] in men, ß=-0.01 [-0.01, -0.00] in women). Conclusion: Central obesity and combined central and general obesity were more strongly positively correlated with lung function. WC-adjusted BMI was negatively correlated with lung function. Body fat percentage was negatively correlated with lung function.

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