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1.
Front Neurosci ; 17: 1176344, 2023.
Article in English | MEDLINE | ID: mdl-37539380

ABSTRACT

Objective: The multi-subject brain-computer interface (mBCI) is becoming a key tool for the analysis of group behaviors. It is necessary to adopt a neural recording system for collaborative brain signal acquisition, which is usually in the form of a fixed wire. Approach: In this study, we designed a wireless group-synchronized neural recording system that supports real-time mBCI and event-related potential (ERP) analysis. This system uses a wireless synchronizer to broadcast events to multiple wearable EEG amplifiers. The simultaneously received broadcast signals are marked in data packets to achieve real-time event correlation analysis of multiple targets in a group. Main results: To evaluate the performance of the proposed real-time group-synchronized neural recording system, we conducted collaborative signal sampling on 10 wireless mBCI devices. The average signal correlation reached 99.8%, the amplitude of average noise was 0.87 µV, and the average common mode rejection ratio (CMRR) reached 109.02 dB. The minimum synchronization error is 237 µs. We also tested the system in real-time processing of the steady-state visual-evoked potential (SSVEP) ranging from 8 to 15.8 Hz. Under 40 target stimulators, with 2 s data length, the average information transfer rate (ITR) reached 150 ± 20 bits/min, and the highest reached 260 bits/min, which was comparable to the marketing leading EEG system (the average: 150 ± 15 bits/min; the highest: 280 bits/min). The accuracy of target recognition in 2 s was 98%, similar to that of the Synamps2 (99%), but a higher signal-to-noise ratio (SNR) of 5.08 dB was achieved. We designed a group EEG cognitive experiment; to verify, this system can be used in noisy settings. Significance: The evaluation results revealed that the proposed real-time group-synchronized neural recording system is a high-performance tool for real-time mBCI research. It is an enabler for a wide range of future applications in collaborative intelligence, cognitive neurology, and rehabilitation.

2.
IEEE Trans Biomed Circuits Syst ; 16(4): 511-523, 2022 08.
Article in English | MEDLINE | ID: mdl-35802543

ABSTRACT

This paper presents a neuromorphic processing system with a spike-driven spiking neural network (SNN) processor design for always-on wearable electrocardiogram (ECG) classification. In the proposed system, the ECG signal is captured by level crossing (LC) sampling, achieving native temporal coding with single-bit data representation, which is directly fed into an SNN in an event-driven manner. A hardware-aware spatio-temporal backpropagation (STBP) is suggested as the training scheme to adapt to the LC-based data representation and to generate lightweight SNN models. Such a training scheme diminishes the firing rate of the network with little plenty of classification accuracy loss, thus reducing the switching activity of the circuits for low-power operation. A specialized SNN processor is designed with the spike-driven processing flow and hierarchical memory access scheme. Validated with field programmable gate arrays (FPGA) and evaluated in 40 nm CMOS technology for application-specific integrated circuit (ASIC) design, the SNN processor can achieve 98.22% classification accuracy on the MIT-BIH database for 5-category classification, with an energy efficiency of 0.75 µJ/classification.


Subject(s)
Neural Networks, Computer , Wearable Electronic Devices , Computers , Electrocardiography
3.
Front Neurosci ; 16: 760298, 2022.
Article in English | MEDLINE | ID: mdl-35495028

ABSTRACT

The spiking neural network (SNN) is a possible pathway for low-power and energy-efficient processing and computing exploiting spiking-driven and sparsity features of biological systems. This article proposes a sparsity-driven SNN learning algorithm, namely backpropagation with sparsity regularization (BPSR), aiming to achieve improved spiking and synaptic sparsity. Backpropagation incorporating spiking regularization is utilized to minimize the spiking firing rate with guaranteed accuracy. Backpropagation realizes the temporal information capture and extends to the spiking recurrent layer to support brain-like structure learning. The rewiring mechanism with synaptic regularization is suggested to further mitigate the redundancy of the network structure. Rewiring based on weight and gradient regulates the pruning and growth of synapses. Experimental results demonstrate that the network learned by BPSR has synaptic sparsity and is highly similar to the biological system. It not only balances the accuracy and firing rate, but also facilitates SNN learning by suppressing the information redundancy. We evaluate the proposed BPSR on the visual dataset MNIST, N-MNIST, and CIFAR10, and further test it on the sensor dataset MIT-BIH and gas sensor. Results bespeak that our algorithm achieves comparable or superior accuracy compared to related works, with sparse spikes and synapses.

4.
IEEE J Biomed Health Inform ; 24(3): 898-906, 2020 03.
Article in English | MEDLINE | ID: mdl-31180873

ABSTRACT

The dental disease is a common disease for a human. Screening and visual diagnosis that are currently performed in clinics possibly cost a lot in various manners. Along with the progress of the Internet of Things (IoT) and artificial intelligence, the internet-based intelligent system have shown great potential in applying home-based healthcare. Therefore, a smart dental health-IoT system based on intelligent hardware, deep learning, and mobile terminal is proposed in this paper, aiming at exploring the feasibility of its application on in-home dental healthcare. Moreover, a smart dental device is designed and developed in this study to perform the image acquisition of teeth. Based on the data set of 12 600 clinical images collected by the proposed device from 10 private dental clinics, an automatic diagnosis model trained by MASK R-CNN is developed for the detection and classification of 7 different dental diseases including decayed tooth, dental plaque, uorosis, and periodontal disease, with the diagnosis accuracy of them reaching up to 90%, along with high sensitivity and high specificity. Following the one-month test in ten clinics, compared with that last month when the platform was not used, the mean diagnosis time reduces by 37.5% for each patient, helping explain the increase in the number of treated patients by 18.4%. Furthermore, application software (APPs) on mobile terminal for client side and for dentist side are implemented to provide service of pre-examination, consultation, appointment, and evaluation.


Subject(s)
Deep Learning , Dental Health Services , Image Interpretation, Computer-Assisted/methods , Telemedicine , Algorithms , Humans , Internet of Things , Software
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