[Primary urothelial carcinoma of the prostate: A case report and review of the literature].

OBJECTIVE: To investigate the clinical diagnosis, treatment and prognosis of primary urothelial carcinoma of the prostate. METHODS: We retrospectively analyzed the clinical data on one case of primary urothelial carcinoma of the prostate and reviewed the relevant published literature. RESULTS: The patient, aged 83 years old and diagnosed with primary urothelial carcinoma of the prostate, was treated by neoadjuvant chemotherapy with gemcitabine plus cisplatin preoperatively, injected with 5-fluorouracil into the cutting edge of the tumor intraoperatively, and pathologically confirmed with high-grade invasive primary urothelial carcinoma of the prostate, followed by adjuvant chemotherapy with gemcitabine plus cisplatin. No recurrence or metastasis was observed during 1-year follow-up. CONCLUSIONS: Primary urothelial carcinoma of the prostate is rare and highly malignant. If the tumor is localized, the patient needs to be treated by neoadjuvant chemotherapy preoperatively, injection with anti-tumor drugs into the cutting edge of the tumor intraoperatively, and adjuvant chemotherapy and regular follow-up postoperatively.

[Comparison of the disposable circumcision stapler, disposable prepuce ligator and traditional surgical method in circumcision].

OBJECTIVE: To compare the effects and complications of the disposable circumcision stapler, disposable prepuce ligator and traditional surgical method in circumcision. METHODS: This retrospective study included 327 cases of phimosis or redundant prepuce treated by circumcision with the disposable circumcision stapler (the DCS group, n = 133), disposable prepuce ligator (the DPL group, n = 105) or traditional surgical method (the TS group, n = 89) in our hospital from June 2019 to June 2020. We compared the three surgical methods in terms of operation time, intraoperative blood loss, pain score, satisfaction of the patients with the penile appearance and incidence rates of incision edema, hematoma, infection and dehiscence. RESULTS: The DCS and DPL groups, compared with the TS group, showed significantly shorter operation time (ï¼»9.72 ± 2.17ï¼½ and ï¼»10.57 ± 2.31ï¼½ vs ï¼»36.13 ± 6.85ï¼½ min, P < 0.01), less intraoperative blood loss (ï¼»2.07 ± 0.96ï¼½ and ï¼»2.53 ± 1.46ï¼½ vs ï¼»14.33 ± 4.92ï¼½ ml, P < 0.01) and higher appearance satisfaction score (4.07 ± 0.80 and 3.93 ± 0.96 vs 3.13 ± 1.06, P < 0.05). The DCS and TS groups, in comparison with the DPL group, exhibited markedly lower pain score (1.87 ± 0.99 and 2.27 ± 1.16 vs 3.87 ± 1.30, P < 0.01) and the rates of postoperative incision hematoma (3.01% and 2.25% vs 9.52%, P < 0.05), and infection and dehiscence (2.45% and 2.04% vs 8.07%, P < 0.05). The postoperative rate of incision edema was remarkably lower in the DCS than in the DPL and CS groups (10.2% vs 20.2% and 23.5%, P < 0.05). CONCLUSIONS: Circumcision with the disposable circumcision stapler, with the advantages of simple operation, short operation time, less bleeding, less pain, satisfactory appearance, and lower incidence of complications, deserves clinical application and promotion.