1.
Chem Pharm Bull (Tokyo)
; 58(12): 1666-8, 2010 Dec.
Article
in English
| MEDLINE
| ID: mdl-21139277
ABSTRACT
A new cembrane diterpenoid, briaviodiol A (1), has been isolated from a soft coral Briareum violacea. The structure of 1 was determined by spectroscopic methods and further confirmed by a single-crystal X-ray diffraction analysis.
Subject(s)
Anthozoa/chemistry , Antineoplastic Agents/chemistry , Diterpenes/chemistry , Animals , Antineoplastic Agents/isolation & purification , Antineoplastic Agents/toxicity , Cell Line, Tumor , Crystallography, X-Ray , Diterpenes/isolation & purification , Diterpenes/toxicity , Humans , Magnetic Resonance Spectroscopy , Molecular Conformation
2.
Chem Pharm Bull (Tokyo)
; 58(5): 662-5, 2010 May.
Article
in English
| MEDLINE
| ID: mdl-20460793
ABSTRACT
Three new 12-hydroxybriarane diterpenoids, excavatoids L-N (1-3), have been isolated from the cultured octocoral Briareum excavatum. The structures of new briaranes 1-3 were elucidated by the interpretations of spectroscopic methods. Excavatoid L (1) displayed moderate inhibitory effects on superoxide anion generation and elastase release by human neutrophils.
