Altered static and dynamic functional brain network in knee osteoarthritis: A resting-state functional magnetic resonance imaging study: Static and dynamic FNC in KOA.

This study aimed to investigate altered static and dynamic functional network connectivity (FNC) and its correlation with clinical symptoms in patients with knee osteoarthritis (KOA). One hundred and fifty-nine patients with KOA and 73 age- and gender-matched healthy subjects (HS) underwent resting-state functional magnetic resonance imaging (rs-fMRI) and clinical evaluations. Group independent component analysis (GICA) was applied, and seven resting-state networks were identified. Patients with KOA had decreased static FNC within the default mode network (DM), visual network (VS), and cerebellar network (CB) and increased static FNC between the subcortical network (SC) and VS (p < 0.05, FDR corrected). Four reoccurring FNC states were identified using k-means clustering analysis. Although abnormalities in dynamic FNCs of KOA patients have been found using the common window size (22 TR, 44 s), but the results of the clustering analysis were inconsistent when using different window sizes, suggesting dynamic FNCs might be an unstable method to compare brain function between KOA patients and HS. These recent findings illustrate that patients with KOA have a wide range of abnormalities in the static and dynamic FNCs, which provided a reference for the identification of potential central nervous therapeutic targets for KOA treatment and might shed light on the other musculoskeletal pain neuroimaging studies.

Microwave Hyperpolarization Effect─An Orthogonal Incoherent Microwave Field Heating Study.

In our previous study, the incoherent combined microwave sources possess a higher water heating rate than a single microwave source. This novel discovery may blaze a new trail in the pursuit of energy conservation. In this paper, a particular orthogonal microwave field device was designed to quantitatively study the effect of incoherent combined microwave heating on 17 solvents. Experimental results indicate that the solvents irradiated with incoherent combined microwaves absorb more microwave energy and experience a faster temperature rise. The multiphysics simulations of water with different microwaves show that the higher heating rate is not caused by the improvement of heating uniformity. In this regard, molecular dynamics simulations of ethanol under the irradiation of incoherent microwave electric fields with perpendicular polarization directions were carried out. The molecular dynamics simulations demonstrate that the main reason for this effect is the higher collision frequency of molecules with incoherent microwave electric fields. This study demonstrates a novel effect of incoherent combined microwave heating and contributes to the development of efficient microwave heating for industrial applications.

Numerical investigation of atmospheric pressure plasma jet under nonuniform electric field.

With the advancement in the understanding of plasma discontinuous structures and the progress of related research, numerical methods for simulating plasmas based on continuous medium approach have encountered significant challenges. In this paper, a numerical model is presented to simulate the motion trajectory of an atmospheric pressure plasma jet under an external nonuniform electric field. The method proposes to treat the plasma jet as equivalent particles with permittivity and conductivity, based on its dielectric properties and motion characteristics. The numerical model demonstrates short calculation times and excellent agreement between simulation results and experimental observations, validating its high efficiency and effectiveness. This work contributes to a deeper understanding of the collective effect of the plasma jet and provides an effective and efficient method for predicting the motion trajectory of the plasma jet, along with guidelines for controlling plasma using external nonuniform electric fields.

Superdirective Wideband Array of Circular Monopoles with Loaded Patches for Wireless Communications.

A wideband superdirective array, composed of a two-element circular monopole configuration, is introduced. The monopoles are placed in close proximity, facing each other on a metal ground. To ensure good matching at high frequencies, two pairs of elliptical patches are added to the sides of the monopoles, enhancing the surface current of the circular patch for wideband performance. To achieve equal amplitude excitation and the desired phase difference, a wideband power divider with a phase shifter is designed to feed the antenna array. Simulation and measurement results demonstrate that the proposed wideband antenna array, operating within the frequency range of 2.94-7.93 GHz, exhibits a maximum directivity of 8.36-10 dBi, with an antenna efficiency ranging from 47.86 to 83.18% across the bandwidth. The proposed array has the advantages of miniaturization, high directivity and wideband operation and can be widely used in various portable wireless communication systems, including WLAN (5.05-5.9 GHz), ISM (5.725-5.875 GHz), 5G communication (3.3-3.8 GHz), etc.

Design of a Microwave Heating and Permittivity Measurement System Based on Oblique Aperture Ridge Waveguide.

In this paper, an oblique aperture ridge waveguide operating at 2450 MHz is proposed, and, using the ridge waveguide, a permittivity measurement system is constructed which can measure the permittivity of materials during microwave heating. The system calculates the amplitudes of the scattering parameters by using the forward, reflected and transmitted powers of the power meters, and it reconstructs the permittivity of the material by combining the scattering parameters with an artificial neural network. The system is used to measure the complex permittivity of mixed solutions of methanol and ethanol with different ratios at room temperature, and the permittivity of methanol and ethanol with increasing temperature, from room temperature to 50 °C. The measured results are in good agreement with the reference data. The system allows simultaneous measurement of the permittivity with microwave heating and provides real-time, rapid changes in the permittivity during heating, avoiding thermal runaway and providing a reference for applications of microwave energy in the chemical industry.

Degree of Coupling in Microwave-Heating Polar-Molecule Reactions.

Microwave-assisted chemical reactions have been widely used, but the overheating effect limits further applications. The aim of this paper is to investigate the coupling degree of the electromagnetic field and thermal field in microwave-heating chemical reactions whose polarization changes as the reactions proceed. First, the entropy-balance equation of microwave-heating polar-molecule reactions is obtained. Then, the coupling degree of the electromagnetic field and the thermal field in microwave-heating polar-molecule reactions is derived, according to the entropy-balance equation. Finally, the effects of reaction processes on the degree of coupling are discussed. When the time scale of the component-concentration variation is much greater than the wave period during the chemical processes, the degree of coupling is sufficiently small, and the electric and thermal fields are considered as weakly coupled. On the other hand, the degree of coupling may change during the reactions. If the absolute value of the coupling degree becomes larger, due to the change in component concentration, this will lead to a transition from weak coupling to strong coupling.

Multidirectional Polarization Impacts on Microwave Heating Efficiency: A Molecular Dynamics Research of Microwave Heating of Common Solvents.

Energy efficiency has always been an inherent problem of microwave heating. In this work, the higher heating efficiency of the elliptically polarized microwave electric field is investigated via MD simulations, aiming to examine the multidirectional polarization effect during microwave heating. The MD results show that the heating efficiency growth rates of EtOH, AcOH, DMSO, H2O, and DMF are 3.17%, 3.92%, 4.14%, 5.00%, and 27.06% sequentially larger with the elliptically polarized microwave electric field (EF) than those with the linearly polarized microwave EF. Energy analyses indicate that the utilization rate of microwave energy would be increased of the elliptically polarized microwave EF with the same electric field intensities. The higher decay speed of the rotation autocorrelation function curves of elliptically polarized EF presents that the sample molecules do have a more frequent rotational motion to align with the varying polarization directions. Additionally, dielectric properties analysis gave the relation between the heating efficiency growth rate and the loss tangent of the samples. This microwave heating method is expected to be a new route to improve the microwave heating efficiency.

Molecular Dynamics Research of Spatial Orientation and Kinetic Energy of Active Site Collision of Carnosine under Weak Microwave Irradiation.

The molecular mechanism of the microwave nonthermal effect is still not clear. This work investigated the spatial orientation and kinetic energy of active site collision of carnosine, a natural bioactive dipeptide, under the weak microwave irradiation using the molecular dynamics simulation. Our results showed the influences of the temperature, microwave intensity, microwave frequency, and microwave polarization mode (linear polarization and circular polarization) on the spatial orientation and kinetic energy of active site collision of carnosine. First, under the constant intensity and frequency of linear polarization microwave irradiation, the increment of the collision probability between the 6N atom of carnosine and the 28H atom of the other carnosine at effective space angle decreases from 85.0% to 3.5% with increasing temperature. Second, with the increase of microwave intensity, the change of spatial orientation and kinetic energy becomes more and more significant. However, the change of circular polarization microwaves on the spatial orientation and kinetic energy of collision is weaker than that of linear polarization. Third, under the constant intensity of linear polarization microwave irradiation, the collision probability between the 6N atom and the 28H atom at effective space angle decreases from 70.2% to 14.7% with increasing frequency. Finally, under the microwave polarization, the spatial orientation and kinetic energy of molecular collision are changed, which is summarized as the microwave postpolarization effect (MWPPE). The dependence of MWPPE on temperature, microwave intensity, microwave frequency, and polarization mode is very complicated. In the end, this effect can provide a new insight into the molecular mechanism of the microwave nonthermal effect.

Investigation of Spatial Orientation and Kinetic Energy of Reactive Site Collision between Benzyl Chloride and Piperidine: Novel Insight into the Microwave Nonthermal Effect.

Microwave nonthermal effect in chemical reactions is still an uncertain problem. In this work, we have studied the spatial orientation and kinetic energy of reactive site collision between benzyl chloride and piperidine molecules in substitution reaction under microwave irradiation using the molecular dynamics simulation. Our results showed that microwave polarization can change the spatial orientation of reactive site collision. Collision probability between the Cl atom of the C-Cl group of benzyl chloride and the H atom of the N-H group of piperidine increased by up to 33.5% at an effective spatial solid angle (θ, φ) of (100∼110°, 170∼190°) under microwave irradiation. Also, collision probability between the C atom of the C-Cl group of benzyl chloride and the N atom of the N-H group of piperidine also increased by up to 25.6% at an effective spatial solid angle (θ, φ) of (85∼95°, 170∼190°). Moreover, the kinetic energy of collision under microwave irradiation was also changed, that is, for the collision between the Cl atom of the C-Cl group and the H atom of the N-H group, the fraction of high-energy collision greater than 6.39 × 10-19 J increased by 45.9 times under microwave irradiation, and for the collision between the C atom of the C-Cl group and the N atom of the N-H group, the fraction of high-energy collision greater than 6.39 × 10-19 J also increased by 29.2 times. Through simulation, the reaction rate increased by 34.4∼50.3 times under microwave irradiation, which is close to the experimental increase of 46.3 times. In the end, spatial orientation and kinetic energy of molecular collision changed by microwave polarization are summarized as the microwave postpolarization effect. This effect provides a new insight into the physical mechanism of the microwave nonthermal effect.

Simultaneous degradation of p-nitrophenol and reduction of Cr(VI) in one step using microwave atmospheric pressure plasma.

Different physicochemical properties between Cr(VI) and phenolic compounds pose serious challenges for the effective treatment of co-contamination. This study developed an electrodeless high-flow microwave atmospheric plasma jet for the single-step simultaneous degradation of p-nitrophenol (PNP) and reduction of Cr(VI). Following a 15 min treatment with microwave atmospheric pressure plasma, the removal efficiency of Cr(VI) and PNP reached 97.5% and 93.6%, respectively, whereas that of total organic carbon reached 30.2%. Adding PNP to the solution significantly improved Cr(VI) reduction, whereas PNP degradation increased slightly with Cr(VI). The results indicate that the PNP intermediates significantly affected Cr(VI) reduction. Additionally, long-lived H2O2 and short-lived ·H aided the reduction of Cr(VI) during plasma treatment. The addition of hydroxyl scavengers during treatment implied that ·OH was largely responsible for PNP oxidation. High-performance liquid chromatography-mass spectroscopy (HPLC-MS) revealed that PNP intermediates, including p-nitrocatechol and 5-nitrobenzene-1,2,3-triol, function as Cr(VI) reductants. On the basis of the examined intermediate products, the potential PNP degradation pathway was investigated. The factors that could influence simultaneous dehgradation and reduction, including solution pH, gas velocity, and distance between the plasma outlet and the water surface were researched. Low pH supports Cr(VI) reduction, and the promotion of PNP for Cr(VI) reduction applies to all pH values. The degradation of PNP is insensitive to pH values with or without Cr(VI). The optimal gas velocity for PNP degradation and Cr(VI) reduction was revealed to be 6 L/min. The simultaneous removal of PNP and Cr(VI) benefits from a shorter distance between the plasma outlet and the water's surface.

Hydrogen Bonding and the Structural Properties of Glycerol-Water Mixtures with a Microwave Field: a Molecular Dynamics Study.

In a microwave field, the dielectric properties, molecular structures, and hydrogen bonding dynamics of glycerol in its mixtures with water were determined by the molecular dynamics simulation method. The dipole-dipole correlation of glycerol is linked to the field intensity of microwaves. The results show that as the field intensity is increased, even glycerol in the second coordination shell can become correlated with each other. The structures of up to 35 glycerol molecules are observed. More than that, it was observed that lifetimes of glycerol-glycerol hydrogen bonds were prolonged, while the average hydrogen bond number was also increased. Besides, the structures in a strong microwave field mimic the weak C-H⋯O hydrogen bonds seen in high-glycerol concentration mixtures, yet the concentration is lower. These results indicate that with the assistance of the microwave field, glycerol molecules become concentrated and are more likely to establish stable interactions with others. As a consequence, the spherical clusters composed by glycerol molecules in our nanosheet synthesis experiment are easier to form.

An electrodeless atmospheric microwave plasma jet for efficient degradation of antibiotic norfloxacin.

Plasma technology is increasingly being used for the degradation of residual antibiotics in aquatic environments. However, the electrodes in conventional plasma generators are subject to erosion, which can pollute the reaction system and shorten its lifetime. To overcome these drawbacks, we developed an electrodeless high-flow atmospheric microwave plasma jet (MPJ) for fast and efficient degradation of residual norfloxacin (NOR), a typical fluoroquinolone antibiotic that is frequently detected in the aquatic environment owing to its widespread use in the treatment of various infectious diseases. Stable plasma was generated through a low-cost magnetron with the assistance of injection-locking technology. The degradation efficiency of NOR (20 mg/L) reached 98.27 ± 1.03% at 6 min and the mineralisation efficiency reached 68.67 ± 3.21% at 15 min. The fast degradation process of the NOR solution contributes to the large cross-section (approximately 153 mm2) of the plasma in direct contact with the solution. Hydroxyl radical (•OH) scavengers were used to identify the generated oxidising species, which indicated that their non-selective oxidation plays a major role in NOR degradation. Three main possible degradation pathways and mechanisms were proposed, namely the attack of •OH on the piperazine ring, quinolone ring, and benzene ring. The NOR solution was not toxic to Escherichia coli after 20 min of degradation. Thus, the high-flow atmospheric MPJ is an effective technology for the degradation of antibiotics in aqueous solutions.

Research on Dry Microwave Heating Infectious Aerosols or Droplets on Respirators.

Dramatic shortages of filtering facepiece respirator supplies generally occur following the outbreak of a pandemic such as COVID-19. Here, the decontamination and reuse of respirators are considered. Among decontamination methods, microwave irradiation has great potential because of easy access of microwave ovens. However, can a respirator be heated in a microwave oven for a certain time and then be reused? Herein, we demonstrate that dry microwave irradiation cannot heat infectious aerosols or droplets up to their deactivation temperature. The microwave absorption performance of a single aerosol or droplet was analyzed theoretically. The multiphysics simulation results indicate that a single aerosol or droplet can be barely heated under dry microwave irradiation. Experiments were carried out using a traveling wave system to verify the simulation. Following this, we simulated multiple aerosols and droplets on a respirator material, with the results indicating that the aerosols and droplets were at the same temperature as that of the respirator. Experimental measurements using a microwave oven demonstrated that the temperature increase of an N95 respirator under dry heating is less than 10 °C, which is far less than the temperature required to deactivate the COVID-19 virus. Although dry microwave heating cannot be used to heat the aerosols or droplets, microwave-generated steam has proved effective in deactivating infectious biological organisms. Therefore, to successfully decontaminate a used respirator in a microwave oven, a reservoir with a small amount of water beneath the respirator (or a steam bag to accommodate it) is essential to the decontamination process.

A self-boosting microwave plasma strategy tuned by air pressure for the highly efficient and controllable surface modification of carbon.

Surface modification is required to improve the activity and compositing ability of carbonaceous materials for their application in numerous areas such as energy storage, aerospace applications, and construction reinforcement. However, current strategies are facing problems such as the involvement of expensive and corrosive chemicals, poor controllability, and breakage of the carbon skeleton, thus sacrificing the mechanical and electrical properties. In this study, a green and controllable self-boosting microwave technology is proposed for the high-efficient surface modification of carbon. Air was used as the only oxidant. A carbon fiber cloth (CFC) is exposed to microwave irradiation in air for 90 s, yielding CFC with a surface oxygen content of 25.73%, 54.41%, and 52.56% at 1 atm, 8000 Pa, and 80 Pa, respectively, as determined via X-ray photoelectron spectroscopy. Notably, the content of each oxygen-containing functional group (e.g., -C-OH and -C[double bond, length as m-dash]O) is controllable by tuning the air pressure. Besides, CFC has enhanced mechanical and electrical properties. In comparison, CFC treated with a strong acid for 2 h only has a surface oxygen content of 21.4%, exhibiting greatly impaired electrical and mechanical properties. Numerical simulations at different pressures suggest that air plasma is triggered and boosted by the existence of CFC at 8000 Pa and 80 Pa, generating different electron number densities and electron temperature distributions, thus resulting in high-efficient and controllable modification.

A microwave atmospheric plasma strategy for fast and efficient degradation of aqueous p-nitrophenol.

Plasma technology has received intensive research interest in pollutants degradation. However, conventional plasma generator suffers from erosion of electrodes and consequent short life time and pollution. In this work, an electrodeless high-flow microwave atmospheric plasma jet is developed for fast degradation of p-nitrophenol. With the assistance of injection locking technology, stable plasma is managed to be generated by low-cost magnetron. 100% removal of 100 mg/L PNP is achieved after 12 min, with a TOC removal efficiency of 57.6%. The fast degradation is probably due to the high cross section (around 153 mm2) of plasma gas. Change in the removal efficiency are less than 4% and 5% as the pH of the solution changes from 2.02 to 12.07 and conductivity varies between 5.38 × 10-2 and 43.6 mS/cm, respectively. Moreover, optical emission spectroscopy spectra of the microwave plasma and a hydroxyl radical scavenger (t-butanol) are employed to identify the generated oxidizing species, which indicates that •OH is the key factor during the degradation process. The hydroxylated intermediates and organic acid transformed from PNP were revealed. Based on the examined intermediate products, the possible degradation mechanism and pathway are analyzed.

Influence of a nearby conductor on shape and length of a microwave plasma jet.

This Rapid Communication reports on the observation of an interesting phenomenon: the shape, especially the length, of a microwave plasma jet (MPJ) can be clearly influenced by simply placing a conductor near the plasma source, particularly when the nearby conductor is in contact with the external conductor of the coaxial microwave plasma generator, accompanied by a significant change in microwave reflection power from the terminal. To further investigate this discovery, the relationships between the length of the plume and some important factors, such as the conductivity and length of the nearby conductor, microwave input power, and gas flow velocity, are analyzed, and we find nonlinear rules of influence of these factors on the jet. Measurements of the electric potential around the jet reveal the nonuniform and non-neutral charge distribution inside the visible plasma plume, which plays a vital role in uncovering the mechanism underlying this phenomenon. The results are helpful for providing a deeper understanding of microwave plasma jet characteristics. More importantly, it provides guidelines to control the MPJ using simple structures.

A High-Temperature Na-Ion Battery: Boosting the Rate Capability and Cycle Life by Structure Engineering.

High-temperature sodium ion batteries (SIBs) have drawn significant heed recently for large-scale energy storage. Yet, conventional SIBs are in the depths of inferior charge/discharge efficiency and cyclability at elevated temperatures. Rational structure design is highly desirable. Hence, a 3D hierarchical flower architecture self-assembled by carbon-coated Na3 V2 (PO4 )3 (NVP) nanosheets (NVP@C-NS-FL) is fabricated via a microwave-assisted glycerol-mediated hydrothermal reaction combined with a post heat-treatment. The growth mechanism of NVP@C-NS-FL is systematically investigated, by forming a microspherical glycerol/polyglycerol-NVP complex initially and then converting into flower-like architecture during the subsequent annealing at a low temperature ramping rate. Benefiting from the integrated structure, fast Na+ transportation, and highly effective heat transfer, the as-obtained NVP@C-NS-FL exhibits an excellent high-temperature SIB performance, e.g., 65 mAh g-1 (100 C) after 1000 cycles under 60 °C. When coupled with NaTi2 (PO4 )3 anode, the full cell can still display superior power capability of 1.4 kW kg-1 and long-term cyclability (2000 cycles) under 60 °C.

Advances in Microwave-Assisted Production of Reduced Graphene Oxide.

Efficient reduction of graphene oxide to obtain high-quality graphene nanosheets is desirable for energy storage, catalysis, electronics and environmental remediation. In this brief review, we mainly focus on the microwave-assisted production of reduced graphene oxide in three categories: (1) microwave-assisted chemical reduction of graphene oxide; (2) microwave-assisted thermal reduction of graphene oxide; (3) microwave-assisted simultaneous thermal exfoliation & thermal reduction of graphite oxide. We also summarize common techniques for characterizing reduction efficiency and quality of as-obtained rGO.

A numerical coupling method for particle tracking in electromagnetic fields.

With the arrival of the information age, the electromagnetic energy in space increases constantly, resulting in the influence of electromagnetic waves on the charged aerosol particles in the environment which should be taken into account. Here, a numerical coupling method based on temporal and spatial scales is proposed to solve the difficulty in obtaining the trajectory of particles under the action of high-frequency electromagnetic waves. In the temporal scale, two constant forces with linear relationship are used to equilibrate the electromagnetic field forces under different conditions, however the above-mentioned equivalent method has the space limitation; in addition, on the spatial scale, the model with larger geometry should be divided into multiple basic modules spatially, the domain division method is adopted and due to the above method it can be used well in the basic module. Verified the correctness through the comparison of the results, and compared with the traditional method, the above method greatly reduces the computational complexity. Some interesting results were obtained by calculating the modulated waves with the above method, which indicate that special forms of electromagnetic waves will significantly affect the motion of particles.

An On-Line System for High Temperature Dielectric Property Measurement of Microwave-Assisted Sintering Materials.

Microwave-assisted sintering materials have been proven to deliver improvements in the mechanical and physicochemical properties of the materials, compared with conventional sintering methods. Accurate values of dielectric properties of materials under high temperatures are essential for microwave-assisted sintering. In view of this, this paper, proposes an on-line system to measure the high temperature dielectric properties of materials under microwave processing at a frequency of 2450 MHz. A custom-designed ridge waveguide is utilized, where samples are heated and measured simultaneously. An artificial neural network (ANN) trained with the corresponding simulation data is integrated into this system to reverse the permittivity of the measured materials. This whole system is tested at room temperature with different materials. Accuracies of measuring dielectric property with an error lower than 9% with respect to theoretical data have been achieved even for high loss media. The functionality of the dielectric measurement system has also been demonstrated by heating and measuring Macor and Duran ceramic glass samples up to 800 °C. All the preliminary experiments prove the feasibility of this system. It provides another method for dielectric property measurement and improves the understanding of the mechanism between microwave and media under high temperatures, which is helpful for optimizing the microwave-assisted sintering of materials.