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Zhong Yao Cai ; 31(6): 880-2, 2008 Jun.
Article in Chinese | MEDLINE | ID: mdl-18998575

ABSTRACT

OBJECTIVE: To investigate the effect of Mailuoning injectable powder on experimental vascular occlusion angeitides in rats. METHODS: Rats were injected laurostearic acid into arteria cruralis to induce the model of experimental vascular occlusion angeitides, then we observed the changes of objective sign of rats, and analysed throm ranking through pathological section under electro-microscope. RESULTS: Mailuoning injectable powder could decrease the quantity of throm in blood vessel, and improve hemorrheoiogy. CONCLUSION: The results show that Mailuoning injectable powder has obvious therapeutical effect on experimental vascular occlusion angeitides in rats, and its mechanism may be related to the anti-throm in blood vessel and improving hemorrheology.


Subject(s)
Drugs, Chinese Herbal/therapeutic use , Phytotherapy , Plants, Medicinal/chemistry , Thromboangiitis Obliterans/drug therapy , Animals , Blood Viscosity/drug effects , Disease Models, Animal , Drug Combinations , Drugs, Chinese Herbal/administration & dosage , Drugs, Chinese Herbal/pharmacology , Hemorheology , Injections, Intravenous , Lauric Acids , Male , Random Allocation , Rats , Rats, Sprague-Dawley , Thromboangiitis Obliterans/chemically induced , Thromboangiitis Obliterans/pathology
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