Translation and psychometric testing of the Chinese version of the Perinatal Missed Care Survey.

Objective: This study aimed to translate and evaluate the psychometric properties of the Perinatal Missed Care Survey in China. Methods: The Perinatal Missed Care Survey was translated according to the guidelines of the cross-cultural debugging scale recommended by the American Academy of Orthopaedic Surgeons Evidence-Based Medicine Committee, including forward translation, back translation, cultural adaption, and content validation, and its Chinese version was used in a cross-sectional study conducted from February to April in 2023. A total of 491 midwives from 14 different level hospitals in southwest China were recruited through a convenience sampling method. The discrimination ability of the items was tested through item analysis, and construct validity was assessed through exploratory factory and confirmatory factor analyses. The content validity index and Cronbach's α coefficients evaluated content validity and reliability, respectively. Results: The Chinese version's item-total correlation coefficients ranged from 0.641 to 0.866 in part A and from 0.644 to 0.819 in part B (P < 0.001). Parts A and B's scale-level content validity indexes were 0.95, and the item-level content validity indexes were from 0.86 to 1.00. The three common factors of part A (necessary care, basic care, and postnatal care) and part B (communication, labor resources, and material resources) were extracted, accounting for 70.186% and 71.984% of the total variance, respectively. Confirmatory factor analysis indicated that the good fit of the three-factor models was acceptable. The Cronbach's α coefficients were 0.968 (part A) and 0.940 (part B). Conclusion: The Chinese version of the Perinatal Missed Care Survey is a reliable and valid instrument for assessing nursing care missed by midwives during labor and birth and the reasons it was missed. Studies with large sample sizes are needed to verify the instrument's applicability in China.

Prevalence and factors associated with trajectories of antenatal depression: a prospective multi-center cohort study in Chengdu, China.

BACKGROUND: Antenatal depression (AD) is a major depressive disorder during pregnancy, which may lead to devastating sequelae for the expectant mothers and infants. This study aimed to investigate the prevalence, to analyze trajectory model based on EPDS score, and to explore the influence factors of AD among pregnant women in Chengdu, China. METHODS: Participants from four maternity hospitals in Chengdu, China were recruited when they had their first pregnancy medical check-up during March 2019 to May 2020. All participants were required to fill in Edinburgh Postnatal Depression Scale Chinese version (EPDS) once during three trimesters and provided information about their health status, social-demographic etc. The trajectory model, chi-square test and multivariate binary logistic regression were used to analyze all collected data. RESULTS: A total of 4560 pregnant women were recruited, while 1051 women completed the study. The prevalence of depression symptoms during the first, second and third trimesters were 32.92% (346/1051), 19.79% (208/1051) and 20.46% (215/1051) respectively. According to the results of the latent growth mixture modeling, the trajectory model of three categories based on EPDS score were identified in this study: low-risk group (38.2%, 401/1051), medium-risk group (54.8%, 576/1051) and high-risk group (7%, 74/1051). Good marital relationship (P = 0.007, OR = 0.33, 95% CI 0.147 ~ 0.74), good relationship with parents-in-law (P = 0.011, OR = 0.561, 95% CI 0.36 ~ 0.874), planned pregnancy (P = 0.018, OR = 0.681, 95% CI 0.496 ~ 0.936) were the protective factors while lower education level (P = 0.036, OR = 1.355, 95% CI 1.02 ~ 1.799), fear about dystocia (P = 0.0, OR = 1.729, 95% CI 1.31 ~ 2.283), recent major negative life events (P = 0.033, OR = 2.147, 95% CI 1.065 ~ 4.329) were the risk factors of medium-risk group. Good marital relationship (P = 0.005, OR = 0.2, 95% CI 0.065 ~ 0.615), good relationship with parents-in-law (P = 0.003, OR = 0.319, 95% CI 0.15 ~ 0.679) were also protective factors of high-risk group, but the risk factors for high-risk group were medical history (P = 0.046, OR = 1.836, 95% CI 1.011 ~ 3.334), pregnancy complications (P = 0.022, OR = 2.015, 95% CI 1.109 ~ 3.662), worry about dystocia (P = 0.003, OR = 2.365, 95% CI 1.347 ~ 4.153), recent major negative life events (P = 0.011, OR = 3.661, 95% CI 1.341 ~ 9.993). No protective or risk factors were identified for low-risk group. CONCLUSION: Even the incidence and levels of depression in the first trimester of pregnancy were the highest, the probability of pregnancy women get depression during gestation period were higher than other population. Therefore, it's important to monitor the psychological status of pregnant women during the whole pregnancy, especially in the first trimester. The study suggested a good partner relationship and good relations with parents-in-law both protected pregnant women from depression and promoted the well-being of mothers and children.

The relationship between alarm fatigue and burnout among critical care nurses: A cross-sectional study.

BACKGROUND: Alarm fatigue has significant negative impacts on nurses and patient safety. However, the relationship between alarm fatigue and burnout is still unclear. AIMS: This study aimed to explore the relationship between alarm fatigue and burnout among critical care nurses. STUDY DESIGN: A descriptive-analytical cross-sectional study design was used. Data were collected from five hospitals in mainland China between January 2022 and March 2022. A general information questionnaire, the Chinese version of the Intensive Care Unit Nurse Alarm Fatigue Questionnaire, and the Chinese version of the Maslach Burnout Inventory were used. RESULTS: A total of 236 critical care nurses were enrolled in this study. The mean score of alarm fatigue among critical care nurses was 21.11 ± 6.83. The results showed that critical care nurses experienced moderate alarm fatigue levels, and most nurses had moderate to high levels of burnout. The multiple linear regression analyses showed that alarm fatigue was independently associated with emotional exhaustion, depersonalization dimensions, and reduced personal accomplishment dimension. CONCLUSIONS: Alarm fatigue was associated with burnout among critical care nurses. Reducing critical care nurses' alarm fatigue may help to alleviate burnout. RELEVANCE TO CLINICAL PRACTICE: Managers should provide comprehensive training for nurses and promote the application of artificial intelligence technology in alarm management to reduce alarm fatigue and improve burnout among critical care nurses.

Synthetic Control of Electronic Property and Porosity in Anthraquinone-Based Conjugated Polymer Cathodes for High-Rate and Long-Cycle-Life Na-Organic Batteries.

Redox-active carbonyl-containing compounds have received extensive attention as cathode materials for sodium-ion batteries (SIBs) because of their excellent attributes, including elemental sustainability, high theoretical capacity, diverse structures, and tunable properties. However, the storage of Na+ in most carbonyl-based cathode materials is plagued by the low capacity, unsatisfying rate performance, and short cycling life. Herein, we develop a series of anthraquinone-based conjugated polymer cathodes consisting of anthraquinone and benzene with different linking patterns. It reveals that the linkage sites on benzene ring could affect the electronic structures of the resulting polymers and thus their charge-storage capabilities. The 1,2,4,5-linkage on benzene leads to a high surface area, a narrow band gap, and the lowest unoccupied molecular orbital for the resulting polymer PBAQ-3. As a cathode for SIBs, it delivers a high capacity of around 200 mAh g-1 and excellent rate performance (105 mAh g-1 at 200 C) as well as stable cycling with a capacity retention of 95.8% after 1000 cycles at 0.05 A g-1 and 83.1% after 40000 cycles at 3 A g-1. Our findings highlight the influence of linking patterns of the building blocks on the electrochemical performance of organic electrodes.

Reliability of Non-Contact Infrared Thermometers for Fever Screening Under COVID-19.

Purpose: Fever is one of the most typical clinical symptoms of coronavirus disease 2019 (COVID-19), and non-contact infrared thermometers (NCITs) are commonly used to screen for fever. However, there is a lack of authoritative data to define a "fever" when an NCIT is used and previous studies have shown that NCIT readings fluctuate widely depending on ambient temperatures and the body surface site screened. The aim of this study was to establish cut-off points for normal temperatures of different body sites (neck, forehead, temples, and wrist) and investigate the accuracy of NCITs at various ambient temperatures to improve the standardization and accuracy of fever screening. Patients and Methods: A prospective investigation was conducted among 904 participants in the outpatient and emergency departments of Chengdu Women's and Children's Central Hospital. Body temperature was measured using NCITs and mercury axillary thermometers. A receiver operating characteristic curve was used to determine the accuracy of body temperature detection at the four body surface sites. Data on participant characteristics were also collected. Results: Among the four surface sites, the neck temperature detection group had the highest accuracy. When the neck temperature was 37.35°C as the optimum fever diagnostic threshold, the sensitivity was 0.866. The optimum fever diagnostic thresholds for forehead, temporal, and wrist temperature were 36.65°C, 36.65°C, and 36.75°C, respectively. Moreover, triple neck temperature detection had the highest sensitivity, up to 0.998, whereas the sensitivity of triple wrist temperature detections was 0.949. Notably, the accuracy of NCITs significantly reduced when the temperature was lower than 18°C. Conclusion: Neck temperature had the highest accuracy among the four NCIT temperature measurement sites, with an optimum fever diagnostic threshold of 37.35°C. Considering the findings reported in our study, we recommend triple neck temperature detection with NCITs as the fever screening standard for COVID-19.

Novel Lytic Phages Protect Cells and Mice against Pseudomonas aeruginosa Infection.

With the fast emergence of serious antibiotic resistance and the lagged discovery of novel antibacterial drugs, phage therapy for pathogenic bacterial infections has acquired great attention in the clinics. However, development of therapeutic phages also faces tough challenges, such as laborious screening and time to generate effective phage drugs since each phage may only lyse a narrow scope of bacterial strains. Identifying highly effective phages with broad host ranges is crucial for improving phage therapy. Here, we isolated and characterized several lytic phages from various environments specific for Pseudomonas aeruginosa by testing their growth, invasion, host ranges, and potential for killing targeted bacteria. Importantly, we identified several therapeutic phages (HX1, PPY9, and TH15) with broad host ranges to lyse laboratory strains and clinical isolates of P. aeruginosa with multi-drug resistance (MDR) both in vitro and in mouse models. In addition, we analyzed critical genetic traits related to the high-level broad host coverages by genome sequencing and subsequent computational analysis against known phages. Collectively, our findings establish that these novel phages may have potential for further development as therapeutic options for patients who fail to respond to conventional treatments.IMPORTANCE Novel lytic phages isolated from various environmental settings were systematically characterized for their critical genetic traits, morphology structures, host ranges against laboratory strains and clinical multi-drug resistant (MDR) Pseudomonas aeruginosa, and antibacterial capacity both in vitro and in mouse models. First, we characterized the genetic traits and compared with other existing phages. Furthermore, we utilized acute pneumonia induced by laboratorial strain PAO1, and W19, an MDR clinical isolate and chronic pneumonia by agar beads laden with FDR1, a mucoid phenotype strain isolated from the sputum of a cystic fibrosis (CF) patient. Consequently, we found that these phages not only suppress bacteria in vitro but also significantly reduce the infection symptom and disease progression in vivo, including lowered bug burdens, inflammatory responses and lung injury in mice, suggesting that they may be further developed as therapeutic agents against MDR P. aeruginosa.

The mental health of Chinese healthcare staff in non-epicenter of COVID-19: a cross-sectional study.

BACKGROUND: The COVID-19 is a public health issue all over the world. It is an unprecedented challenge for society. Frontline medical staff are at high risk of mental health problems due to the overwhelming workload, worry of infection, and inadequate protective instruments. The study is to investigate the psychological status of medical staff in a women and children's hospital in non-epicenter of COVID-19 during the early stage of the COVID-19 outbreak. METHODS: A total of 2,143 hospital medical staff participated in a cross-sectional online survey. Psychological response levels were assessed using the Psychological Questionnaire on Emergency Events in Public Health (PQEEPH), and mental health status was measured using the Generalized Anxiety Disorder-7 (GAD-7) scale. RESULTS: Eligible responses were received from 1,890 (90.6%) women and 197 (9.4%) men. In total, 10.3% of respondents rated the psychological impact of the outbreak as moderate or severe, and 4% reported severe anxiety symptoms. CONCLUSIONS: Our findings indicated that the majority of the medical staff are in great level of mental health. The study demonstrates that females, the 31-40 age group, and those who have been widowed experienced greater levels of anxiety and therefore require more support. Furthermore, the cognition of medical workers might affect their emotional reactions. Measures to decrease anxiety during emergency outbreaks should therefore include communication strategies.

[Analysis on possibilities of multi-spectral data for quantitative retrieving soil nutrition element contents].

Models for predicting soil nutrition elements content were established by regression methods. The data source was simulated multi-spectral data from reflectance spectra measured under laboratory condition. First, the reflectance spectra were resampled to the corresponding bands of multi-spectral sensors (TM and ASTER) according to their reflectance response functions. Then, the experiential models were established between measured spectra, simulated reflectance spectra (TM and ASTER) and soil nutrition element contents by stepwise multiple linear regression (SMLR) and partial least square regression (PLSR) methods. Precision of these models was tested by validation soil samples. Compared with models established by measured spectra, precision of simulated spectra models is slightly affected by spectral resolution. Simulated spectra models give good results for nitrogen (R = 0.89), phosphor (R = 0.79), and potassium (R = 0.68). The selected band range of SMLR models for soil N, P, and K are 2 000 to 2 300 nm, 1 650 to 1 800 nm and 600 to 800 nm respectively. The coefficients of PLSR models show that near infrared (NIR) band is more sensitive to nitrogen and phosphor than visible (VIS) band, while VIS is better for potassium. Good prediction performance indicates theoretically the future possibilities of multivariate calibration for soil nutrition element concentrations by multi-spectral remotely sensed images and bands character of sensors should be considered well because different element has different response.

[Mid- to long-term effects of delayed percutaneous coronary intervention on left ventricular function and prognosis in patients with acute myocardial infarction].

OBJECTIVE: To investigate the mid- to long-term effects of delayed percutaneous coronary intervention (PCI) on the left ventricular function and clinical outcome of patients with acute myocardial infarction (AMI). METHODS: PCI (including percutaneous transluminal coronary angioplasty and stenting) was performed in 42 patients within 1 to 2 weeks following the onset of AMI (PCI group), with another 31 patients who were admitted within the same period to receive medication for AMI serving as the control group. The patients in both groups were observed for comparison of the occurrence of reinfarction and angina, mortality at 1 and 6 months, and findings by ultrasound cardiograms (UCG). RESULTS: In PCI group, the left ventricular function were obviously improved as compared with the control group (P<0.01) 1 month after the onset of AMI, showing greater improvement at 6 months (P<0.01). No death or reinfarction occurred in the PCI group, with only 1 patients experiencing angina 5 months after PCI. In control group, death occurred in 2 cases, reinfarction in 1 case, recurrent angina in 4 cases (include 2 cases of early postinfarction angina). CONCLUSION: Delayed PCI may significantly improve the prognosis of patients with AMI and prolong their survival without cardiovascular accidents and ameliorate their left ventricular functions, with high success rate of the operation.