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1.
J Radiol ; 90(5 Pt 1): 553-9, 2009 May.
Article in French | MEDLINE | ID: mdl-19503043

ABSTRACT

Until recently, the optimal work-up of patients with stable coronary artery disease (CAD) was based on non-invasive functional tests. Coronary CTA (CCTA) now challenges this standard work-up due to its efficacy to exclude significant coronary artery disease. Current indications for CCTA include symptomatic patients with intermediate pre-test probability of CAD with altered ECG (LBBB, repolarization abnormalities) rendering stress tests useless or patients unable to achieve sustained stress effort, and patients with indeterminate or uninterpretable results on ischemic work-up. A more agressive position is to consider CCTA as the cornerstone of patient management because the limitations and pitfalls of non-invasive techniques open the door to an alternative diagnostic imaging technique, either alone, or in combination with other Imaging techniques after reorganizing the sequence of imaging work-up. Without dismissing the dogma of initial détection of CAD along with prognostic stratification using functional tests, the recent availability of a minimally invasive anatomical test in the management of patients with stress angina, given the known limitations of traditional tests, changes the standard work-up algorithms. This suggests that the diagnostic work-up of patients with CAD is likely to be modified to increase the rôle of CCTA.


Subject(s)
Coronary Angiography , Coronary Artery Disease/diagnostic imaging , Image Processing, Computer-Assisted , Imaging, Three-Dimensional , Radiographic Image Enhancement , Tomography, X-Ray Computed , Adult , Aged , Algorithms , Angina Pectoris/diagnostic imaging , Angina Pectoris/therapy , Coronary Artery Disease/therapy , Electrocardiography , Exercise Test , Female , Humans , Male , Middle Aged , Myocardial Revascularization , Prognosis , Sensitivity and Specificity , Signal Processing, Computer-Assisted
2.
J Radiol ; 85(10 Pt 2): 1798-808, 2004 Oct.
Article in French | MEDLINE | ID: mdl-15507835

ABSTRACT

The advent of helical multidetector CT has significantly modified several traditional clinical approaches to cardiovascular diagnosis. The current availability of rapid image acquisition has provided the basis for investigating direct imaging in real time of cardiac structures using CT. Application of thin-section submillimetric image acquisitions to three-dimensional (3D) reconstruction algorithms produces 3D data sets from which images of the coronary arteries may be obtained in any anatomic plane. The advantage of the submillimetric isotropic spatial resolution is partly offset by reduced temporal resolution as well as reduced contrast resolution compared to MRI. This lack in contrast sensitivity prevents accurate perfusion imaging and restricts the clinical use to coronary artery imaging. Moreover, the large amount of iodinated contrast medium injected has potential nephrotoxic effects, which can be deleterious if coronary artery angiography must to be performed. On the other hand, MRI has less spatial resolution, and acquisitions must be performed in the plane of each coronary artery because of reduced volume coverage. Both techniques play a role in the non-invasive assessment of coronary artery disease, by providing complementary information already useful in a growing number of clinical situations.


Subject(s)
Coronary Angiography , Coronary Artery Disease/diagnosis , Magnetic Resonance Imaging , Tomography, X-Ray Computed , Coronary Angiography/methods , Female , Humans , Magnetic Resonance Imaging/methods , Male , Tomography, X-Ray Computed/methods
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