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Molecules ; 16(12): 9783-91, 2011 Nov 25.
Article in English | MEDLINE | ID: mdl-22117169

ABSTRACT

Quercetin and quercetin glycosides are physiologically active flavonol molecules that have been attributed numerous health benefits. Recovery of such molecules from plant matrices depends on a variety of factors including polarity of the extraction solvent. Among the solvents of a wide range of dielectric constants, methanol recovered the most quercetin and its glycosides from dehydrated 'Idared' apple peels. When ultra-sonication was employed to facilitate the extraction, exposure of 15 min of ultrasound wavelengths of dehydrated apple peel powder in 80% to 100% (v/v) methanol in 1:50 (w:v) solid to solvent ratio provided the optimum extraction conditions for quercetin and its glycosides. Acidification of extraction solvent with 0.1% (v/v) or higher concentrations of HCl led to hydrolysis of naturally occurring quercetin glycosides into the aglycone as an extraction artifact.


Subject(s)
Glycosides/isolation & purification , Malus/chemistry , Plant Extracts/isolation & purification , Quercetin/isolation & purification , Solvents/chemistry , Sonication/methods , Ultrasonics/methods , Hydrochloric Acid/chemistry , Methanol/chemistry , Time Factors , Waste Products
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