ABSTRACT
Transjugular liver biopsy is an alternative of percutaneous biopsy in collection of hepatic tissue for histological examination. It is used when percutaneous biopsy is contraindicated, or involves great risk, i.e. in particular in patients with severe ascites and severely impaired blood coagulation. According to worldwide statistics it occurs in about one third of hepatological patients. The authors present a group of 16 patients who had transjugular biopsy and report on the high yield and low risk of the method. A representative histological sample was obtained in 100%, there were no complications in the investigated group. The authors give an account of the indications and description of the method, its possible complications. They compare their results with data in the literature. Their initial experience confirms that the inclusion of transjugular biopsy among hepatological examination methods is justified.
Subject(s)
Biopsy, Needle/methods , Liver/pathology , Adult , Female , Humans , Jugular Veins , Male , Middle AgedABSTRACT
Spinal muscular atrophy, type I-III and Duchenne muscular dystrophy belong to the most frequent neuromuscular diseases in children. The purpose of this work was to determine the incidence of these two diseases in liveborn children in the years 1975 to 1989 in the south part of middle Slovakia. The common incidence of all three types of spinal muscular atrophy was 1 in 5631 liveborn children (most frequent was the Werdnig-Hoffmann disease, type I--1 in 12,286). This fact confirms, that this disease belongs to the most frequent autosomal recessive diseases in children of our region too. The incidence of Duchenne muscular dystrophy was 1 in 4827 liveborn boys. The figure is in the range of the published data of the incidence of this disease. The deletion in the dystrofin gene was proved in 70% of affected boys. (Tab. 3, Fig. 1, Ref. 24).
Subject(s)
Muscular Atrophy, Spinal/epidemiology , Muscular Dystrophies/epidemiology , Child , Female , Humans , Incidence , Male , Slovakia/epidemiology , Spinal Muscular Atrophies of Childhood/epidemiologySubject(s)
Cystic Fibrosis/pathology , Autopsy , Cystic Fibrosis/diagnosis , Humans , Infant , Infant, NewbornSubject(s)
Ethics, Medical , Philosophy, Medical , Physician-Patient Relations , Psychiatry , Humans , Social ResponsibilityABSTRACT
Solar heating of dense natural brines to 47 degrees C has been observed in a small lagoon in the Venezuelan Antilles and in an artificial brine reservoir in New York State. Calculations indicate that approximately 90 percent of the solar energy can be trapped in the brine by a combination of refraction and absorption. Brine ponds should be considered as solar energy collectors.
ABSTRACT
An electrophoretic variant of beta-glucuronidase is present in certain inbred mouse lines. The variant simultaneously affects the mobility of the lysosomal and microsomal forms of the enzyme. The difference is inherited as a single gene mapping at the position of the structural gene on chromosome 5. This confirms that beta-glucuronidase at both intracellular sites is coded by the same structural gene.
